Evidence map›Paper›PMID 27372453›Full record

ReviewEuropean journal of nutrition2016

Sugar addiction: the state of the science.

Margaret L Westwater, Paul C Fletcher, Hisham Ziauddeen

Open access · hybridAbstract readComparative StudyReview
In one paragraph

Review in European journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.

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  11. Applying psycho-behavioural phenotyping in obesity characterization.Reviews in endocrine & metabolic disorders · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Margaret L WestwaterBrain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, CB2 3EB, UK.
Paul C FletcherDepartment of Psychiatry, Addenbrooke's Hospital, University of Cambridge, Herchel Smith Building, Cambridge, CB2 0SZ, UK.
Hisham ZiauddeenDepartment of Psychiatry, Addenbrooke's Hospital, University of Cambridge, Herchel Smith Building, Cambridge, CB2 0SZ, UK. hz238@cam.ac.uk.
Addenbrooke's Hospital · GBUniversity of Cambridge · GB

Funding

Medical Research Council MC_UU_12012/5Wellcome Trust 093875
6 · The paper itself

Abstract

purposeAs obesity rates continue to climb, the notion that overconsumption reflects an underlying 'food addiction' (FA) has become increasingly influential. An increasingly popular theory is that sugar acts as an addictive agent, eliciting neurobiological changes similar to those seen in drug addiction. In this paper, we review the evidence in support of sugar addiction.

methodsWe reviewed the literature on food and sugar addiction and considered the evidence suggesting the addictiveness of highly processed foods, particularly those with high sugar content. We then examined the addictive potential of sugar by contrasting evidence from the animal and human neuroscience literature on drug and sugar addiction.

resultsWe find little evidence to support sugar addiction in humans, and findings from the animal literature suggest that addiction-like behaviours, such as bingeing, occur only in the context of intermittent access to sugar. These behaviours likely arise from intermittent access to sweet tasting or highly palatable foods, not the neurochemical effects of sugar.

conclusionGiven the lack of evidence supporting it, we argue against a premature incorporation of sugar addiction into the scientific literature and public policy recommendations.

Indexed as

Behavior, AddictiveDietary SucroseAnimalsBinge-Eating DisorderDietary FatsDisease Models, AnimalFoodGlycemic IndexGlycemic LoadHumansMotivationObesityReceptors, Dopamine D2Substance-Related DisordersDietary FatsDietary SucroseReceptors, Dopamine D2Animal neuroscienceBinge eatingDrug addictionObesitySugar addiction

Identifiers

PMID27372453
PMCPMC5174153
OpenAlexW2462952368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.