Evidence map›Paper›PMID 27372270›Full record

ArticleAmerican journal of obstetrics and gynecology2016

Proposed diagnostic criteria for the case definition of amniotic fluid embolism in research studies.

Steven L Clark, Roberto Romero, Gary A Dildy, William M Callaghan, Richard M Smiley, Arthur W Bracey, Gary D Hankins, Mary E D'Alton, Mike Foley, Luis D Pacheco and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
30.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 181 citations in OpenAlex.

  1. Echocardiography findings in amniotic fluid embolism: a systematic review of the literature.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Steven L ClarkBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX. Electronic address: slclark@bcm.edu.
Roberto RomeroBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Gary A DildyBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
William M CallaghanBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Richard M SmileyBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Arthur W BraceyBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Gary D HankinsBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Mary E D'AltonBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Mike FoleyBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Luis D PachecoBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Rakesh B VadheraBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
J Patrick HerlihyBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Richard L BerkowitzBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Michael A BelfortBaylor College of Medicine, Houston, TX; Perinatology Research Branch of the Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Detroit, MI, and Bethesda, MD; Columbia University, New York, NY; Centers for Disease Control and Prevention, Atlanta, GA; Banner Health, Phoenix, AZ; University of Texas Medical Branch, Galveston, TX.
Baylor College of Medicine · USBanner Health · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USThe University of Texas Medical Branch at Galveston · USColumbia University · USNational Institutes of Health · US

Funding

The Role Of Subclinical Infection And Cytokines In Preterm ParturitionZIAHD002400 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROMERO, ROBERTO · 2009 to 2025
$254.4M
Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Amniotic fluid embolism is a leading cause of maternal mortality in developed countries. Our understanding of risk factors, diagnosis, treatment, and prognosis is hampered by a lack of uniform clinical case definition; neither histologic nor laboratory findings have been identified unique to this condition. Amniotic fluid embolism is often overdiagnosed in critically ill peripartum women, particularly when an element of coagulopathy is involved. Previously proposed case definitions for amniotic fluid embolism are nonspecific, and when viewed through the eyes of individuals with experience in critical care obstetrics, would include women with a number of medical conditions much more common than amniotic fluid embolism. We convened a working group under the auspices of a committee of the Society for Maternal-Fetal Medicine and the Amniotic Fluid Embolism Foundation whose task was to develop uniform diagnostic criteria for the research reporting of amniotic fluid embolism. These criteria rely on the presence of the classic triad of hemodynamic and respiratory compromise accompanied by strictly defined disseminated intravascular coagulopathy. It is anticipated that limiting research reports involving amniotic fluid embolism to women who meet these criteria will enhance the validity of published data and assist in the identification of risk factors, effective treatments, and possibly useful biomarkers for this condition. A registry has been established in conjunction with the Perinatal Research Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development to collect both clinical information and laboratory specimens of women with suspected amniotic fluid embolism in the hopes of identifying unique biomarkers of this condition.

Indexed as

Biomedical ResearchCongresses as TopicDiagnosis, DifferentialEmbolism, Amniotic FluidFemaleHumansPractice Guidelines as TopicPregnancyamniotic fluid embolismcritical care

Identifiers

PMID27372270
PMCPMC5072279
OpenAlexW2462001482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.