Evidence map›Paper›PMID 27371387›Full record

ArticleIntegrative and comparative biology2016

The Metronome of Symbiosis: Interactions Between Microbes and the Host Circadian Clock.

Elizabeth A C Heath-Heckman

Open access · bronzeAbstract read
In one paragraph

Article in Integrative and comparative biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Molecular Interactions between Pathogens and the Circadian Clock.International journal of molecular sciences · 2019
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elizabeth A C Heath-HeckmanDepartment of Molecular and Cell Biology, University of California - Berkeley, Berkeley, CA 94720, USA heathheckman@berkeley.edu.
University of California, Berkeley · US

Funding

Elucidating molecular mechanisms mediating cellular responses to touch and painF32NS095665 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEATH-HECKMAN, ELIZABETH A. · 2015 to 2017
$108k
NINDS NIH HHS F32 NS095665
6 · The paper itself

Abstract

The entrainment of circadian rhythms, physiological cycles with a period of about 24 h, is regulated by a variety of mechanisms, including nonvisual photoreception. While circadian rhythms have been shown to be integral to many processes in multicellular organisms, including immune regulation, the effect of circadian rhythms on symbiosis, or host-microbe interactions, has only recently begun to be studied. This review summarizes recent work in the interactions of both pathogenic and mutualistic associations with host and symbiont circadian rhythms, focusing specifically on three mutualistic systems in which this phenomenon has been best studied. One important theme taken from these studies is the fact that mutualisms are profoundly affected by the circadian rhythms of the host, but that the microbial symbionts in these associations can, in turn, manipulate host rhythms. The interplay between circadian rhythms and symbiosis is a promising new field with effects that should be kept in mind when designing future studies across biology.

Indexed as

Circadian ClocksMicrobiological PhenomenaSymbiosisAnimalsHost-Pathogen Interactions

Identifiers

PMID27371387
PMCPMC6080420
OpenAlexW2475356379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.