ArticleProceedings of the National Academy of Sciences of the United States of America2016
Sympatric speciation of spiny mice, Acomys, unfolded transcriptomically at Evolution Canyon, Israel.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 26 citations in OpenAlex.
- Genomic and evolutionary evidence for drought adaptation of allopolyploid Brachypodium hybridum.Journal of experimental botany · 2025Article
- Scattered differentiation of unlinked loci across the genome underlines ecological divergence of the selfing grassProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Mammalian organ regeneration in spiny mice.Journal of muscle research and cell motility · 2023Review
- Sympatric or micro-allopatric speciation in a glacial lake? Genomic islands support neither.National science review · 2022Article
- Incipient Sympatric Speciation and Evolution of Soil Bacteria Revealed by Metagenomic and Structured Non-Coding RNAs Analysis.Biology · 2022Article
- Sympatric speciation of the spiny mouse from Evolution Canyon in Israel substantiated genomically and methylomically.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Multi-Omics Analysis Reveals the Mechanism Underlying the Edaphic Adaptation in Wild Barley at Evolution Slope (Tabigha).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Incipient sympatric speciation in wild barley caused by geological-edaphic divergence.Life science alliance · 2020Article
- Transcriptome-Wide Patterns of the Genetic and Expression Variations in Two Sympatric Schizothoracine Fishes in a Tibetan Plateau Glacier Lake.Genome biology and evolution · 2020Article
- Geographic contrasts between pre- and postzygotic barriers are consistent with reinforcement in Heliconius butterflies.Evolution; international journal of organic evolution · 2019Article
- Aggression and courtship differences found in Drosophila melanogaster from two different microclimates at Evolution Canyon, Israel.Scientific reports · 2019Article
- Range-constrained co-occurrence simulation reveals little niche partitioning among rock-dwellingJournal of biogeography · 2018Article
- Adaptive Transcriptome Profiling of Subterranean Zokor, Myospalax baileyi, to High- Altitude Stresses in Tibet.Scientific reports · 2018Article
- Transcriptomes Divergence ofFrontiers in genetics · 2018Article
- Population Genomics Reveals Speciation and Introgression between Brown Norway Rats and Their Sibling Species.Molecular biology and evolution · 2017Article
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Authors and funding
8 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spiny mice, Acomys cahirinus, colonized Israel 30,000 y ago from dry tropical Africa and inhabited rocky habitats across Israel. Earlier, we had shown by mtDNA that A. cahirinus incipiently sympatrically speciates at Evolution Canyon I (EC I) in Mount Carmel, Israel because of microclimatic interslope divergence. The EC I microsite consists of a dry and hot savannoid "African" slope (AS) and an abutting humid and cool-forested "European" slope (ES). Here, we substantiate incipient SS in A. cahirinus at EC I based on the entire transcriptome, showing that multiple slope-specific adaptive complexes across the transcriptome result in two divergent clusters. Tajima's D distribution of the abutting Acomys interslope populations shows that the ES population is under stronger positive selection, whereas the AS population is under balancing selection, harboring higher genetic polymorphisms. Considerable sites of the two populations were differentiated with a coefficient of FST = 0.25-0.75. Remarkably, 24 and 37 putatively adaptively selected genes were detected in the AS and ES populations, respectively. The AS genes involved DNA repair, growth arrest, neural cell differentiation, and heat-shock proteins adapting to the local AS stresses of high solar radiation, drought, and high temperature. In contrast, the ES genes involved high ATP associated with energetics stress. The sharp ecological interslope divergence led to strong slope-specific selection overruling the interslope gene flow. Earlier tests suggested slope-specific mate choice. Habitat interslope-adaptive selection across the transcriptome and mate choice substantiate sympatric speciation (SS), suggesting its prevalence at EC I and commonality in nature.
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