Evidence map›Paper›PMID 27369695›Full record

ArticleThe journal of physiological sciences : JPS2017

The role of apelin in the healing of water-immersion and restraint stress-induced gastric damage.

İlknur Birsen, Burcu Gemici, Nuray Acar, İsmail Üstünel, V Nimet İzgüt-Uysal

Open access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

İlknur BirsenDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.
Burcu GemiciDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.
Nuray AcarDepartment of Histology and Embryology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.
İsmail ÜstünelDepartment of Histology and Embryology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.
V Nimet İzgüt-UysalDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey. nimetu@akdeniz.edu.tr.
Akdeniz University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to explore the role of apelin in the healing of gastric lesions induced by stress. Male Wistar rats were exposed to water immersion and restraint stress (WIRS) for 6 h with or without the apelin receptor antagonist F13A. The rats were killed on the 1st, 3rd, 5th or 10th day after the end of stress induction. Apelin and hypoxia-inducible factor-1α expression was increased on the 1st day after the end of stress exposure and was decreased daily thereafter. However, F13A retarded the healing of gastric lesions by preventing the improvement of mucosal blood flow, prostaglandin E

Indexed as

AnimalsApelinDehydrationGastric MucosaHypoxia-Inducible Factor 1, alpha SubunitImmersionIntercellular Signaling Peptides and ProteinsMaleMalondialdehydeNitric OxideRatsRats, WistarRestraint, PhysicalStomachStress, PhysiologicalVascular Endothelial Growth Factor AApelinApln protein, ratHypoxia-Inducible Factor 1, alpha SubunitIntercellular Signaling Peptides and ProteinsMalondialdehydeNitric OxideVascular Endothelial Growth Factor AWaterApelinF13AGastric mucosaLesionWater immersion and restraint stress

Identifiers

PMID27369695
PMCPMC10717744
OpenAlexW2474515229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.