Evidence map›Paper›PMID 27368095›Full record

ArticleCell2016

Evidence of G.O.D.'s Miracle: Unearthing a RAG Transposon.

Martin F Flajnik

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. A cold-blooded view of adaptive immunity.Nature reviews. Immunology · 2018
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Martin F FlajnikDepartment of Microbiology and Immunology, University of Maryland Baltimore, 685 West Baltimore St., Suite 380, Baltimore, MD 21201, USA. Electronic address: mflajnik@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Evolution of Adaptive ImmunityR01OD010549 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI FLAJNIK, MARTIN F · 2013 to 2017
$1.7M
NIH HHS R01 OD010549
6 · The paper itself

Abstract

Diversity of antibodies and T cell receptors is generated by gene rearrangement dependent on RAG1 and RAG2, enzymes predicted to have been derived from a transposable element (TE) that invaded an immunoglobulin superfamily gene early in the evolution of jawed vertebrates. Now, Huang et al. report the discovery of ProtoRAG in the lower chordate Amphioxus, the long-anticipated TE related to the RAG transposon.

Indexed as

Evolution, MolecularAnimalsDNA-Binding ProteinsDNA Transposable ElementsGene RearrangementHomeodomain ProteinsHumansVertebratesDNA-Binding ProteinsDNA Transposable ElementsHomeodomain Proteins

Identifiers

PMID27368095
PMCPMC5428540
OpenAlexW2468857765

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.