ArticleSocial science & medicine (1982)2016
Education and alcohol use: A study of gene-environment interaction in young adulthood.
Article in Social science & medicine (1982), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Causal effects of education attainment on oral and oropharyngeal cancer: New evidence from a meta-analysis and Mendelian randomization study.Frontiers in public health · 2023Pooled it
- Engaging migrants and immigrants in genetics research.Nature genetics · 2025Review
- Genetic and environmental influences on alcohol consumption in middle to late life.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Article
- Etiology and correlates of alcohol misuse in early midlife.Alcohol, clinical & experimental research · 2025Article
- Uric acid index is a risk for mild cognitive impairment in type 2 diabetes.Hormones (Athens, Greece) · 2023Observational
- Predictive Factors for the Necessity of Hospitalization of Patients With Acute Alcohol Intoxication.Journal of clinical medicine research · 2023Article
- Variations of Brain Functional Connectivity in Alcohol-Preferring and Non-Preferring Rats with Consecutive Alcohol Training or Acute Alcohol Administration.Brain sciences · 2021Article
- Educational inequalities in mental disorders in the Czech Republic: data from CZEch Mental health Study (CZEMS).Social psychiatry and psychiatric epidemiology · 2021Article
- Aggressive-Depressive Trajectories in Childhood and Their Associations with Drinking Behaviors and Problems in Adolescence and Emerging Adulthood.Journal of youth and adolescence · 2020Article
- Which adolescent factors predict alcohol misuse in young adulthood? A co-twin comparisons study.Addiction (Abingdon, England) · 2020Article
- The epidemiology of alcohol use disorders cross-nationally: Findings from the World Mental Health Surveys.Addictive behaviors · 2020Article
- FinnTwin12 Cohort: An Updated Review.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Review
- Polygenic risk for alcohol misuse is moderated by romantic partnerships.Addiction (Abingdon, England) · 2019Article
- Socioeconomic Status and Adolescent Alcohol Involvement: Evidence for a Gene-Environment Interaction.Journal of studies on alcohol and drugs · 2018Article
- Childhood socioeconomic status and longitudinal patterns of alcohol problems: Variation across etiological pathways in genetic risk.Social science & medicine (1982) · 2018Article
- Social Relationships Moderate Genetic Influences on Heavy Drinking in Young Adulthood.Journal of studies on alcohol and drugs · 2017Article
- Cultural Value Orientations and Alcohol Consumption in 74 Countries: A Societal-Level Analysis.Frontiers in psychology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
The consequences of heavy alcohol use remain a serious public health problem. Consistent evidence has demonstrated that both genetic and social influences contribute to alcohol use. Research on gene-environment interaction (GxE) has also demonstrated that these social and genetic influences do not act independently. Instead, certain environmental contexts may limit or exacerbate an underlying genetic predisposition. However, much of the work on GxE and alcohol use has focused on adolescence and less is known about the important environmental contexts in young adulthood. Using data from the young adult wave of the Finnish Twin Study, FinnTwin12 (N = 3402), we used biometric twin modeling to test whether education moderated genetic risk for alcohol use as assessed by drinking frequency and intoxication frequency. Education is important because it offers greater access to personal resources and helps determine one's position in the broader stratification system. Results from the twin models show that education did not moderate genetic variance components and that genetic risk was constant across levels of education. Instead, education moderated environmental variance so that under conditions of low education, environmental influences explained more of the variation in alcohol use outcomes. The implications and limitations of these results are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.