Evidence map›Paper›PMID 27367744›Full record

ArticleEye (London, England)2016

Risk factors for intraoperative floppy iris syndrome: a prospective study.

I P Chatziralli, V Peponis, E Parikakis, A Maniatea, E Patsea, P Mitropoulos, Medscape

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Iris color as a predictive factor for intraoperative floppy iris syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  5. Floppy iris syndrome associated with specific medication intake: A narrative review.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023
    Review
  6. Preoperative atropine and non-steroidal anti-inflammatory drugs for the prevention of intraoperative floppy iris syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  7. Observational
  8. Article
  9. Review
  10. Preoperative ocular characteristics predicting the development of intraoperative floppy iris syndrome regardless of alpha-antagonist exposure status.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Intraoperative Floppy Iris Syndrome: Updated Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Silodosin-associated intraoperative floppy iris syndrome.Indian journal of ophthalmology · 2017
    Article
  19. Intraoperative floppy iris syndrome and its association with various concurrent medications, bulbus length, patient age and gender.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

I P Chatziralli2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
V Peponis2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
E Parikakis2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
A Maniatea2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
E Patsea2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
P Mitropoulos2nd Department of Ophthalmology, Ophthalmiatrion Athinon, Athens, Greece.
Medscape
Athens Eye Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeTo evaluate risk factors for intraoperative floppy iris syndrome (IFIS) in patients undergoing phacoemulsification.MethodsParticipants in the study were 1274 consecutive patients, who underwent routine phacoemulsification cataract surgery. The following data were recorded and evaluated as possible risk factors: ophthalmological conditions, axial length of the eye, sociodemographic features, clinical data (hypertension and diabetes mellitus), medications being taken at the time of surgery, and duration of their intake. Cases were characterized intraoperatively as IFIS and non-IFIS. Univariate and multivariate logistic regression analysis were performed.ResultsIFIS was observed in 63/1274 eyes (4.9%, 95% CI: 3.9-6.7%). Current use of tamsulosin, alfuzosin, terazosin, benzodiazepines, quetiapine, and finasteride, as well as hypertension, were all independently associated with IFIS. Significant associations were noted for male sex, rivastigmine, and short axial length, which did not reach significance at the multivariate analysis. Duration of α-blockers intake was not found to be associated with IFIS.ConclusionApart from the well-established associations with α-blockers, this prospective study points to benzodiazepines, quetiapine, finasteride, and hypertension as potential risk factors for IFIS. Short axial length and rivastigmine were significantly associated with IFIS only at the univariate analysis.

Indexed as

Intraoperative ComplicationsLens Implantation, IntraocularPhacoemulsificationAdrenergic alpha-1 Receptor AntagonistsAgedAged, 80 and overAxial Length, EyeBenzodiazepinesFemaleFinasterideHumansHypertensionIris DiseasesMaleProspective StudiesQuetiapine FumarateAdrenergic alpha-1 Receptor AntagonistsBenzodiazepinesFinasterideQuetiapine Fumarate

Identifiers

PMID27367744
PMCPMC4985673
OpenAlexW2472349624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.