Evidence map›Paper›PMID 27366715›Full record

ArticleIndian journal of endocrinology and metabolism

Comparison of maternal and fetal outcomes among Asian Indian pregnant women with or without gestational diabetes mellitus: A situational analysis study (WINGS-3).

Manni Mohanraj Mahalakshmi, Balaji Bhavadharini, Kumar Maheswari, Gunasekaran Kalaiyarasi, Ranjit Mohan Anjana, Unnikrishnan Ranjit, Viswanathan Mohan, Kurian Joseph, Kurian Rekha, Sivagnanam Nallaperumal and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Comparison of Maternal and Fetal Outcomes in Parturients With and Without a Diagnosis of Gestational Diabetes.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Manni Mohanraj MahalakshmiDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Balaji BhavadhariniDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Kumar MaheswariDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Gunasekaran KalaiyarasiDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Ranjit Mohan AnjanaDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Unnikrishnan RanjitDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Viswanathan MohanDepartment of Epidemiology and Diabetology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India.
Kurian JosephDepartment of Obstetrics and Gynecology, Joseph Nursing Home, Chennai, Tamil Nadu, India.
Kurian RekhaDepartment of Obstetrics and Gynecology, Joseph Nursing Home, Chennai, Tamil Nadu, India.
Sivagnanam NallaperumalDepartment of Diabetology, Prashanth Infertility Research Centre, Chennai, Tamil Nadu, India.
Belma MalandaDepartment of Policy and Programmes, International Diabetes Federation, Brussels, Belgium.
Arivudainambi KayalDepartment of Policy and Programmes, International Diabetes Federation, Brussels, Belgium.
Anne BeltonDepartment of Policy and Programmes, International Diabetes Federation, Brussels, Belgium.
Ram UmaDepartment of Obstetrics and Gynecology, Seethapathy Clinic and Hospital, Chennai, Tamil Nadu, India.
Madras Diabetes Research Foundation · INInternational Diabetes Federation · BESeethapathy Clinic and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the existing maternal and fetal outcomes in Asian Indian women with or without gestational diabetes mellitus (GDM) before the development of the Women in India with GDM Strategy (WINGS) GDM model of care (MOC). MATERIALS AND

methodsRecords of pregnant women were extracted retrospectively from three maternity centers in Chennai. GDM was diagnosed using the International Association for Pregnancy Study Groups criteria or the Carpenter and Coustan criteria. Demographic details, obstetric history, antenatal follow-up, treatment for GDM, and outcomes of delivery were collected from the electronic medical records.

resultsOf the 3642 records analyzed, 799 (21.9%) had GDM, of whom 456 (57.1%) were treated with insulin and medical nutrition therapy (MNT), 339 (42.4%) with MNT alone, and 4 (0.5%) with metformin. Women with GDM were older than those without (28.5 ± 4.5 vs. 27.1 ± 4.5 years; P < 0.001) and had higher mean body mass index at first booking (26.4 ± 5.2 kg/m(2) vs. 25.2 ± 5.1 kg/m(2); P < 0.001). Rates of cesarean section (26.2% vs. 18.7%; P < 0.001), preeclampsia (1.8% vs. 0.8%; P = 0.04), and macrosomia (13.9% vs. 10.8%; P = 0.02) were significantly higher among women with GDM. In women with GDM treated with insulin and MNT, emergency cesarean section (16.2% vs. 36.6%; P < 0.0001), preeclampsia (0.7% vs. 3.2%; P = 0.015), and macrosomia (9.9% vs. 18.6%; P = 0.0006) were significantly lesser compared to those treated with MNT alone.

conclusionPregnancy outcomes were in general worse in GDM women. Treatment with insulin was associated with a significantly lower risk of complications. However, in countries with limited access to insulin and other medicines may lead to poor follow-up and management of GDM. Data from this retrospective study will form the basis for the development of the WINGS GDM MOC, which will address these gaps in GDM care in low-resource settings.

Indexed as

Asian Indiansfetal outcomesgestational diabetes mellitusmaternal outcomesSouth Asians

Identifiers

PMID27366715
PMCPMC4911838
OpenAlexW2419186351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.