ArticleJournal of intercultural ethnopharmacology
In vitro antimicrobial activity of five essential oils on multidrug resistant Gram-negative clinical isolates.
Article in Journal of intercultural ethnopharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Antimicrobial, Antioxidant, and Immunomodulatory Properties of Essential Oils: A Systematic Review.Nutrients · 2019Pooled it
- Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review.BMC veterinary research · 2019Pooled it
- Antibacterial and anti-biofilm activities of thyme oil, oregano oil, and their combination against Klebsiella pneumoniae and Acinetobacter baumannii polymicrobial biofilms.Antonie van Leeuwenhoek · 2026Article
- Essential Oils as Antimicrobial Agents Against WHO Priority Bacterial Pathogens: A Strategic Review of In Vitro Clinical Efficacy, Innovations and Research Gaps.Antibiotics (Basel, Switzerland) · 2025Review
- Influence of Hyptis suaveolens growth stage on essential oil composition, antimicrobial and antioxidant activities.Scientific reports · 2025Article
- Influence of growth stage on the chemical composition, antimicrobial, and antioxidant potential ofFrontiers in plant science · 2025Article
- To Evaluate and Compare the Antimicrobial Efficacy of Various Disinfecting Agents on K-file against Gram-positive and Gram-negative Bacteria of Endodontic Origin: AnInternational journal of clinical pediatric dentistry · 2023Article
- Assessing Contact Time and Concentration ofAntibiotics (Basel, Switzerland) · 2023Article
- A New Lavender (Life (Basel, Switzerland) · 2022Article
- Facing Resistant Bacteria with Plant Essential Oils: Reviewing the Oregano Case.Antibiotics (Basel, Switzerland) · 2022Review
- Microbiological Quality of Deer Meat Treated with Essential OilAnimals : an open access journal from MDPI · 2022Article
- Antitumor Effect ofMolecules (Basel, Switzerland) · 2022Article
- Progress in Alternative Strategies to Combat Antimicrobial Resistance: Focus on Antibiotics.Antibiotics (Basel, Switzerland) · 2022Review
- Essential Oils from Indigenous Iranian Plants: A Natural Weapon vs. Multidrug-ResistantMicroorganisms · 2022Article
- Essential Oils: A Natural Weapon against Antibiotic-Resistant Bacteria Responsible for Nosocomial Infections.Antibiotics (Basel, Switzerland) · 2021Article
- A Review of the Phytochemistry and Antimicrobial Properties ofIranian journal of pharmaceutical research : IJPR · 2021Review
- Origanum vulgare essential oil: antibacterial activities and synergistic effect with polymyxin B against multidrug-resistant Acinetobacter baumannii.Molecular biology reports · 2020Article
- Identification of Essential Oils Including Garlic Oil and Black Pepper Oil with High Activity againstPathogens (Basel, Switzerland) · 2020Article
- In Vitro Activity of Essential Oils Against Planktonic and Biofilm Cells of Extended-Spectrum β-Lactamase (ESBL)/Carbapenamase-Producing Gram-Negative Bacteria Involved in Human Nosocomial Infections.Antibiotics (Basel, Switzerland) · 2020Article
- Essential Oils with High Activity against Stationary PhaseAntibiotics (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIM/
backgroundThe emergence of drug-resistant pathogens has drawn attention on medicinal plants for potential antimicrobial properties. The objective of the present study was the investigation of the antimicrobial activity of five plant essential oils on multidrug resistant Gram-negative bacteria. MATERIALS AND
methodsBasil, chamomile blue, origanum, thyme, and tea tree oil were tested against clinical isolates of Acinetobacter baumannii (n = 6), Escherichia coli (n = 4), Klebsiella pneumoniae (n = 7), and Pseudomonas aeruginosa (n = 5) using the broth macrodilution method.
resultsThe tested essential oils produced variable antibacterial effect, while Chamomile blue oil demonstrated no antibacterial activity. Origanum, Thyme, and Basil oils were ineffective on P. aeruginosa isolates. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration values ranged from 0.12% to 1.50% (v/v) for tea tree oil, 0.25-4% (v/v) for origanum and thyme oil, 0.50% to >4% for basil oil and >4% for chamomile blue oil. Compared to literature data on reference strains, the reported MIC values were different by 2SD, denoting less successful antimicrobial activity against multidrug resistant isolates.
conclusionsThe antimicrobial activities of the essential oils are influenced by the strain origin (wild, reference, drug sensitive, or resistant) and it should be taken into consideration whenever investigating the plants' potential for developing new antimicrobials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.