Evidence map›Paper›PMID 27366280›Full record

ArticleAsian journal of neurosurgery

Pleomorphic xanthoastrocytoma with anaplastic features: A rare case report and review of literature with reference to current management.

M R Patibandla, Madhukar Nayak, A K Purohit, Amit Kumar Thotakura, Megha Uppin, Sundaram Challa

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Asian journal of neurosurgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

M R PatibandlaDepartment of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Madhukar NayakDepartment of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
A K PurohitDepartment of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Amit Kumar ThotakuraDepartment of Neurosurgery, NRI Medical College, Mangalagiri, Andhra Pradesh, India.
Megha UppinDepartment of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Sundaram ChallaDepartment of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Nizam's Institute of Medical Sciences · INNRI Medical College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleomorphic xanthoastrocytoma (PXA) is an uncommon tumor constitutes less than 1% of all astrocytic glial neoplasms was first reported in 1979. PXA commonly occurs in young patients and manifests itself first as seizures followed by focal neurological deficits. The role of radiotherapy or chemotherapy has not yet been established because of the relative infrequency of this disease. PXA is classified as grade II tumor in the WHO classification of tumors of the CNS. In literature 9 to 20 % PXA may undergo malignant change at recurrence or may display at the time of initial presentation. Malignant transformation is mainly associated with high mitotic activity and necrosis. The criteria for PXA with anaplastic features was five or more mitotic activity per 10 high power fields, necrosis, microvascular proliferation, marked cellular anaplasia, and high Ki-67 labeling indices. PXA with anaplastic features management is highly controversial as very sparse literature is available. We are reporting a case of PXA with anaplastic features with atypical radiology and tried to review the up to date literature regarding this rare tumor.

Indexed as

astrocytomamanagement of PXAPleomorphic xanthoastrocytomaPXA with anaplasia

Identifiers

PMID27366280
PMCPMC4849322
OpenAlexW2318478843

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.