Evidence map›Paper›PMID 27366218›Full record

ArticleTherapeutic advances in gastroenterology2016

The association between socioeconomic status and the symptoms at diagnosis of celiac disease: a retrospective cohort study.

Abhik Roy, Shilpa Mehra, Ciarán P Kelly, Sohaib Tariq, Kumar Pallav, Melinda Dennis, Ann Peer, Benjamin Lebwohl, Peter H R Green, Daniel A Leffler

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Factors influencing diagnostic delays in celiac disease.World journal of gastroenterology · 2025
    Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Review
  16. Physicians' attitude and perception regarding celiac disease: A questionnaire-based study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2018
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abhik RoyDepartment of Gastroenterology, Columbia University, 622 West 168th Street, PH7 West (Room 318), New York, NY 10032, USA.
Shilpa MehraDivision of Gastroenterology and Hepatology, Montefiore Medical Center, Bronx, NY, USA.
Ciarán P KellyDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Sohaib TariqDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Kumar PallavDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Melinda DennisDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Ann PeerDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Benjamin LebwohlDepartment of Gastroenterology, Columbia University, New York, NY, USA.
Peter H R GreenDepartment of Gastroenterology, Columbia University, New York, NY, USA.
Daniel A LefflerDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are little data on patient factors that impact diagnosis rates of celiac disease. This study aims to evaluate the association between patient socioeconomic status and the symptoms at diagnosis of celiac disease.

methodsA total of 872 patients with biopsy-proven celiac disease were categorized based on the presence or absence of (1) diarrhea and (2) any gastrointestinal symptoms at diagnosis. Univariate and multivariate analyses were used to assess the association between socioeconomic status and symptoms.

resultsPatients without diarrhea at presentation had a higher mean per capita income (US$34,469 versus US$32,237, p = 0.02), and patients without any gastrointestinal symptoms had a higher mean per capita income (US$36,738 versus US$31,758, p < 0.01) compared with patients having such symptoms. On multivariable analysis adjusting for sex, age, autoimmune or psychiatric comorbidities, and income, per capita income remained a significant predictor of diagnosis without gastrointestinal symptoms (odds ratio: 1.71, 95% confidence interval: 1.17-2.50, p < 0.01), and it showed a trend towards significance in diagnosis without diarrhea (odds ratio: 1.40, 95% confidence interval: 0.98-2.02, p = 0.06).

conclusionsPatients with nonclassical symptoms of celiac disease are less likely to be diagnosed if they are of lower socioeconomic status. Celiac disease may be under-recognized in this population due to socioeconomic factors that possibly include lower rates of health-seeking behavior and access to healthcare.

Indexed as

diarrheagluten-free diethealthcare disparityincome

Identifiers

PMID27366218
PMCPMC4913330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.