ReviewInternational journal of chronic obstructive pulmonary disease2016
The asthma-COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease?
Review in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Asthma and Tobacco Smoking.Journal of personalized medicine · 2022Review
- Eosinophilic endotype of chronic obstructive pulmonary disease: similarities and differences from asthma.The Korean journal of internal medicine · 2021Review
- Asthma-COPD overlap: current understanding and the utility of experimental models.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- A Role for Mucolytics and Expectorants in Aiding Inhaled Therapies in Asthma? [Response To Letter].Journal of inflammation research · 2021Article
- Medication Adherence in a Community Population with Uncontrolled Asthma.Pharmacy (Basel, Switzerland) · 2020Article
- Effect of Pulmonary Rehabilitation in Patients with Asthma COPD Overlap Syndrome: A Randomized Control Trial.Oman medical journal · 2020Article
- Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink).Journal of asthma and allergy · 2019Article
- Impact of COPD diagnosis timing on clinical and economic outcomes: the ARCTIC observational cohort study.International journal of chronic obstructive pulmonary disease · 2019Observational
- Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort.Respiratory research · 2018Article
- Prevalence and management of severe asthma in primary care: an observational cohort study in Sweden (PACEHR).Respiratory research · 2018Observational
- Use of clinical characteristics to predict spirometric classification of obstructive lung disease.International journal of chronic obstructive pulmonary disease · 2018Article
- Sex and racial/ethnic differences in the reason for 30-day readmission after COPD hospitalization.Respiratory medicine · 2017Article
- When is dual bronchodilation indicated in COPD?International journal of chronic obstructive pulmonary disease · 2017Review
- Prevalence and characteristics of asthma-COPD overlap syndrome identified by a stepwise approach.International journal of chronic obstructive pulmonary disease · 2017Observational
- Article
- Incidence and long-term outcome of severe asthma-COPD overlap compared to asthma and COPD alone: a 35-year prospective study of 57,053 middle-aged adults.International journal of chronic obstructive pulmonary disease · 2017Article
- Airflow obstruction: is it asthma or is it COPD?International journal of chronic obstructive pulmonary disease · 2016Review
- Current situation of asthma-COPD overlap in Chinese patients older than 40 years with airflow limitation: a multicenter, cross-sectional, non-interventional study.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term asthma-COPD overlap syndrome (ACOS) is one of multiple terms used to describe patients with characteristics of both COPD and asthma, representing ~20% of patients with obstructive airway diseases. The recognition of both sets of morbidities in patients is important to guide practical treatment decisions. It is widely recognized that patients with COPD and coexisting asthma present with a higher disease burden, despite the conceptual expectation that the "reversible" or "treatable" component of asthma would allow for more effective management and better outcomes. However, subcategorization into terms such as ACOS is complicated by the vast spectrum of heterogeneity that is encapsulated by asthma and COPD, resulting in different clinical clusters. In this review, we discuss the possibility that these different clusters are suboptimally described by the umbrella term "ACOS", as this additional categorization may lead to clinical confusion and potential inappropriate use of resources. We suggest that a more clinically relevant approach would be to recognize the extreme variability and the numerous phenotypes encompassed within obstructive airway diseases, with various degrees of overlapping in individual patients. In addition, we discuss some of the evidence to be considered when making practical decisions on the treatment of patients with overlapping characteristics between COPD and asthma, as well as the potential options for phenotype and biomarker-driven management of airway disease with the aim of providing more personalized treatment for patients. Finally, we highlight the need for more evidence in patients with overlapping disease characteristics and to facilitate better characterization of potential treatment responders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.