ArticleJournal of neurosciences in rural practice
Morphological spectrum of peripheral nerve sheath tumors: An insight into World Health Organization 2013 classification.
Article in Journal of neurosciences in rural practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Intra-cerebellar schwannoma with various degenerative changes: a case report and a systematic review.BMC neurology · 2022Pooled it
- Hemorrhagic lumbar synovial cyst mimicking a neoplastic process: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- A Rare Case of Diffuse Extra-Cranial Schwannomatosis of the Trunk and Limbs.Clinical case reports · 2026Article
- Pathological Fracture in the Metatarsal Bone Due to an Intraosseous Schwannoma: A Case Report.Cureus · 2025Article
- Clinical Findings and Outcome in 30 Dogs with Presumptive or Confirmed Nerve Sheath Tumors.Veterinary sciences · 2024Article
- Left distal sciatic giant solitary myxoid neurofibroma: a case report & literature review.Frontiers in surgery · 2024Article
- Article
- Trigeminal Nerve Melanotic Schwannoma in Carney Complex.The Indian journal of radiology & imaging · 2022Article
- Case Report: A Novel Lateral Approach to the C7, C8, and T1 Intervertebral Foramina for Resection of Malignant Peripheral Nerve Sheath Neoplasia, Followed by Adjunctive Radiotherapy, in Three Dogs.Frontiers in veterinary science · 2022Article
- Dermatological and endocrine elements in Carney complex (Review).Experimental and therapeutic medicine · 2021Review
- A case of peripancreatic plexiform schwannoma.Surgical case reports · 2021Article
- A clinicopathological study of peripheral schwannomas.Medicine and pharmacy reports · 2021Article
- Relationship between magnetic resonance imaging findings and histological grade in spinal peripheral nerve sheath tumors in dogs.Journal of veterinary internal medicineArticle
- An update on oral peripheral nerve sheath tumors.Journal of oral and maxillofacial pathology : JOMFPReview
- A solitary giant neurofibroma of inguinal region: A case report.Science progressArticle
- Histopathologic and Immunohistochemical Analysis of Neurofibromas in a North-Western Nigerian Tertiary Hospital: A Ten-Year Retrospective Study.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
- Histopathological and Immunohistochemical Patterns of Malignant Peripheral Nerve Sheath Tumours in a Tertiary Institution of Northern Nigeria.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
- Histomorphological Spectrum and Diagnostic Utility of S100, SOX10, CD34, Calretinin, and Ki67 in the Evaluation of Schwannomas: A Retrospective Study of 26 Cases in a Tertiary Health Institute, Zaria-Nigeria.Journal of the West African College of SurgeonsArticle
- Clinical and pathological features of upper limb nerve tumors - four years retrospective study.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeripheral nerve sheath tumors (PNSTs) are neuroectodermal in origin. Now these tumors are classified under World Health Organization (WHO) classification of tumors of soft tissue and bone 2013.
objectiveTo study the morphological spectrum of PNST and to study the secondary degenerative changes associated with it. MATERIALS AND
methodsThis study was conducted from January 2010 to June 2015. The gross details of tumor and patient's demographic profiles were reviewed. The hematoxylin and eosin stained slides were reassessed and the lesions were categorized and classified as per the WHO 2013 classification. The tumors were also assessed for secondary degenerative changes.
resultsOur study comprised 143 cases of PNST. Age of the patients ranged from 5 to 75 years. 21-30 years is the most common age of occurrence with head and neck being the most common site. The PNSTs observed in the present study were neurofibroma (NF) (61.5%), schwannoma (36%), malignant PNST (2%), and granular cell tumor (0.5%). Nearly 10% of NF fulfilled the criteria for neurofibromatosis 1 (NF1). Rare tumors such as plexiform schwannoma and granular cell tumor were also observed. Malignant tumors were larger in dimension than benign. Myxoid, cystic, and hyaline changes were commonly associated with benign tumors while necrosis, hemorrhage, and mitotic activity were seen with malignant tumors.
conclusionThis series highlights the pathological variants of PNST along with their morphological changes and NF1 association. It is essential to be familiar with all these variants of PNST for accurate diagnosis as they have varied biological behavior.
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