ArticleHuman reproduction (Oxford, England)2016
Prevalence of infertility and help seeking among 15 000 women and men.
Article in Human reproduction (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 185 papers, 17 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
185 citing papers in PubMed, 17 syntheses or guidelines pooled it.
- Epidemiology of infertility and coping mechanisms in Ethiopia, 2025: a systematic review and meta-analysis.Reproductive health · 2025Pooled it
- Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2025Pooled it
- Prevalence and contributing factors of depression among women with infertility in low-resource settings: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- MTHFR C677T、MTHFR A1298C、MTRR A66G and MTR A2756G polymorphisms and male infertility risk: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2024Pooled it
- The Prevalence of Complementary and Alternative Medicine Use among Infertile Patients: A Global Systematic Review and Meta-Analysis.International journal of fertility & sterility · 2024Pooled it
- Economic evaluations of assisted reproductive technologies in high-income countries: a systematic review.Human reproduction (Oxford, England) · 2024Pooled it
- Trends in acupuncture for infertility: a scoping review with bibliometric and visual analysis.Frontiers in endocrinology · 2024Pooled it
- Ovulation induction drug and ovarian cancer: an updated systematic review and meta-analysis.Journal of ovarian research · 2023Pooled it
- Advanced Sperm Selection Strategies as a Treatment for Infertile Couples: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- The Association of Sperm DNA Fragment and Assisted Reproductive Outcomes: A Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- An Overview of Systematic Reviews of Acupuncture for Infertile Women UndergoingFrontiers in public health · 2021Pooled it
- A Systematic Review and Meta-Analysis of Male Infertility and the Subsequent Risk of Cancer.Frontiers in oncology · 2021Pooled it
- Tubal flushing for subfertility.The Cochrane database of systematic reviews · 2020Pooled it
- Psychosocial Consequences of Female Infertility in Iran: A Meta-Analysis.Frontiers in psychiatry · 2020Pooled it
- Interventions for unexplained infertility: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2019Pooled it
- The effects of acupuncture on pregnancy outcomes of in vitro fertilization: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2019Pooled it
- Female alcohol consumption and fecundability: a systematic review and dose-response meta-analysis.Scientific reports · 2017Pooled it
- The clinical effectiveness of the Mind/Body Program for Infertility on wellbeing and assisted reproduction outcomes: a randomized controlled trial in search for active ingredients.Human reproduction (Oxford, England) · 2024Trial
- Beetroot, watermelon and ginger juice supplementation may increase the clinical outcomes of Intracytoplasmic Sperm Injection cycles.JBRA assisted reproduction · 2023Trial
- Proof of concept and development of a couple-based machine learning model to stratify infertile patients with idiopathic infertility.Scientific reports · 2021Trial
125 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
study questionWhat is the prevalence of infertility and of help seeking among women and men in Britain? SUMMARY ANSWER: One in eight women and one in ten men aged 16-74 years had experienced infertility, defined by unsuccessfully attempting pregnancy for a year or longer, and little more than half of these people sought medical or professional help. WHAT IS KNOWN ALREADY: Estimates of infertility and help seeking in Britain vary widely and are not easily comparable because of different definitions and study populations. STUDY DESIGN, SIZE, DURATION: A cross-sectional population survey was conducted between 2010 and 2012 with a sample of 15 162 women and men aged 16-74 years. PARTICIPANTS/MATERIALS, SETTING,
methodsParticipants completed the Natsal-3 questionnaire, using computer-assisted personal interviewing (CAPI) and computer-assisted self-interview (CASI). MAIN RESULTS AND THE ROLE OF CHANCE: The reported prevalence of infertility was 12.5% (CI 95% 11.7-13.3) among women and 10.1% (CI 95% 9.2-11.1) among men. Increased prevalence was associated with later cohabitation with a partner, higher socio-economic status and, for those who had a child, becoming parents at older ages. The reported prevalence of help seeking was 57.3% (CI 95% 53.6-61.0) among women and 53.2% (CI 95% 48.1-58.1) among men. Help seekers were more likely to be better educated and in higher status occupations and, among those who had a child, to have become parents later in life. LIMITATIONS, REASONS FOR CAUTION: These data are cross-sectional so it is not possible to establish temporality or infer causality. Self-reported data may be subject to recall bias. WIDER IMPLICATIONS OF THE
findingsThe study provides estimates of infertility and help seeking in Britain and the results indicate that the prevalence of infertility is higher among those delaying parenthood. Those with higher educational qualifications and occupational status are more likely to consult with medical professionals for fertility problems than others and these inequalities in help seeking should be considered by clinical practice and public health. STUDY FUNDING/COMPETING INTERESTS: Funding was provided by grants from the Medical Research Council and the Wellcome Trust, with support from the Economic and Social Research Council and the Department of Health. AMJ is a Governor of the Wellcome Trust. Other authors have no competing interests.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.