SynthesisChinese medical journal2016
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration versus Standard Bronchoscopic Modalities for Diagnosis of Sarcoidosis: A Meta-analysis.
Synthesis in Chinese medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Pooled it
- Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Reply to: Revisiting the reported superiority of endobronchial ultrasound (EBUS)-guided transbronchial mediastinal cryobiopsy over EBUS-guided transbronchial needle aspiration in sarcoidosis.ERJ open research · 2026Article
- Diagnostic value of EBUS-guided transbronchial mediastinal cryobiopsyERJ open research · 2026Article
- Diagnostic Value of EBUS-guided Transbronchial MEdiastinal Cryobiopsy versus ConvenTIONal Bronchoscopic Approaches for Intrathoracic Stage I/II SARcoidosis: protocol for a randomised controlled trial (DETECTION-SAR-II).BMJ open respiratory research · 2026Article
- Impact of Rapid Cytologic Evaluation of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration on the Value of Adjunctive Transbronchial Biopsy in Sarcoidosis.CHEST pulmonary · 2026Article
- Scoping out sarcoidosis: the evolving role of bronchoscopy.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- The Role of Bronchoscopy in the Diagnosis of Interstitial Lung Disease: A State-of-the-Art Review.Journal of clinical medicine · 2025Review
- Impact of Pulmonary and Critical Care Fellow Participation during Advanced Diagnostic Bronchoscopy.ATS scholar · 2025Observational
- Serum soluble interleukin-2 receptor level is a predictive marker for EBUS-TBNA-based diagnosis of sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2020Article
- Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB)-technical review.Journal of thoracic disease · 2019Review
- Role of Bronchoscopic Techniques in the Diagnosis of Thoracic Sarcoidosis.Journal of clinical medicine · 2019Review
- A pragmatic application of endobronchial ultrasound-guided transbronchial needle aspiration: a single institution experience.BMC pulmonary medicine · 2019Article
- Management of neurosarcoidosis: a clinical challenge.Current opinion in neurology · 2019Review
- Age is an independent predictor in pathological diagnosis of sarcoidosis: a retrospective analysis of diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration.Journal of thoracic disease · 2019Article
- Role of Convex Probe Endobronchial Ultrasound in the Diagnosis and Treatment of Nonmalignant Diseases.Pulmonary medicine · 2019Review
- Diagnostic Yield of Transbronchial Biopsy in Comparison to High Resolution Computerized Tomography in Sarcoidosis CasesAsian Pacific journal of cancer prevention : APJCP · 2018Article
- The role of endobronchial ultrasound versus mediastinoscopy for non-small cell lung cancer.Journal of thoracic disease · 2017Review
- Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsyEndoscopic ultrasoundArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an effective technique used to precisely detect enlarged mediastinal lymph nodes. The efficacy of EBUS-TBNA versus standard modalities for the diagnosis of sarcoidosis remains to be elucidated. In this meta-analysis, we compared the efficacies of these methods.
methodsWe searched PubMed, Embase, The Cochrane Library, Wanfang, Cpvip, CNKI, and the bibliographies of the relevant references. We analyzed the data obtained with Revman 5.2 (Nordic Cochrane Center, Copenhagen, Denmark) and Stata 12.0 software (Stata Corporation, College Station, TX, USA). The Mantel-Haenszel method was used to calculate the pooled odds ratio (OR) and 95% confidence intervals (CIs).
resultsSixteen studies with a total of 1823 participants met the inclusion criteria, and data were extracted regarding the diagnostic yield of each approach. The ORs for EBUS-TBNA versus transbronchial lung biopsy (TBLB) for the diagnosis of sarcoidosis ranged from 0.26 to 126.58, and the pooled OR was 5.89 (95% CI, 2.20-15.79, P = 0.0004). These findings indicated that EBUS-TBNA provided a much higher diagnostic yield than TBLB. The pooled OR for EBUS-TBNA + TBLB + endobronchial biopsy (EBB) versus TBNA + TBLB + EBB was 1.54 (95% CI, 0.61-3.93, P = 0.36), implying that there was no significant difference between their diagnostic yields. However, clinical heterogeneity was reflected in the nature of the studies and in the operative variables.
conclusionsThe results of this meta-analysis suggest that EBUS-TBNA + TBLB + EBB could be used for the diagnosis of sarcoidosis, if available. At medical centers without EBUS-TBNA, TBNA + TBLB + EBB could be used instead.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.