Evidence map›Paper›PMID 27364750›Full record

ArticlePediatric surgery international2016

Pancreatic surgery for tumors in children and adolescents.

Maria G Sacco Casamassima, Colin D Gause, Seth D Goldstein, Fizan Abdullah, Avner Meoded, Jeffrey R Lukish, Christopher L Wolfgang, John Cameron, David J Hackam, Ralph H Hruban and 1 more

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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  16. A retrospective analysis of pancreas operations in children.Translational gastroenterology and hepatology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Maria G Sacco CasamassimaDivision of Pediatric Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
Colin D GauseDivision of Pediatric Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
Seth D GoldsteinDivision of Pediatric Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
Fizan AbdullahDivision of Pediatric Surgery, Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Avner MeodedDivision of Pediatric Radiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
Jeffrey R LukishDivision of Pediatric Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
Christopher L WolfgangDepartment of Surgery, The Sol Goldman Pancreatic Research Center, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
John CameronDepartment of Surgery, The Sol Goldman Pancreatic Research Center, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
David J HackamDivision of Pediatric Surgery, The Johns Hopkins School of Medicine, Baltimore, MD, USA.
Ralph H HrubanDepartment of Pathology, The Sol Goldman Pancreatic Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Paul M ColombaniDepartment of Surgery, Johns Hopkins All Children's Hospital, 601 5th Street South, Suite 501, Saint Petersburg, FL, 33701, USA. pc@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · USJohns Hopkins All Children's Hospital · USLurie Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePancreatic neoplasms are uncommon in children. This study sought to analyze the clinical and pathological features of surgically resected pancreatic tumors in children and discuss management strategies.

methodsWe conducted a retrospective review of patients ≤21 years with pancreatic neoplasms who underwent surgery at a single institution between 1995 and 2015.

resultsNineteen patients were identified with a median age at operation of 16.6 years (IQR 13.5-18.9). The most common histology was solid pseudopapillary neoplasm (SPN) (n = 13), followed by pancreatic neuroendocrine tumor (n = 3), serous cystadenoma (n = 2) and pancreatoblastoma (n = 1). Operative procedures included formal pancreatectomy (n = 17), enucleation (n = 1) and central pancreatectomy (n = 1). SPNs were noninvasive in all but one case with perineural, vascular and lymph node involvement. Seventeen patients (89.5 %) are currently alive and disease free at a median follow-up of 5.7 (IQR 3.7-10.9) years. Two patients died: one with metastatic insulinoma and another with SPN who developed peritoneal carcinomatosis secondary to a concurrent rectal adenocarcinoma.

conclusionsPediatric pancreatic tumors are a heterogeneous group of neoplastic lesions for which surgery can be curative. SPN is the most common histology, is characterized by low malignant potential and in selected cases can be safely and effectively treated with a tissue-sparing resection and minimally invasive approach.

Indexed as

AdolescentChemotherapy, AdjuvantCystadenoma, SerousFemaleHumansMaleNeuroendocrine TumorsPancreatectomyPancreatic NeoplasmsRetrospective StudiesChildrenPancreatic neoplasmPancreatic neuroendocrine tumorPancreatoblastomaPediatricSolid pseudopapillary tumor

Identifiers

PMID27364750
OpenAlexW2462076131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.