Evidence map›Paper›PMID 27364608›Full record

ArticleBioorganic & medicinal chemistry2016

Structural effects of modified ribonucleotides and magnesium in transfer RNAs.

You Xu, Alexander D MacKerell, Lennart Nilsson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic & medicinal chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

You XuDepartment of Biosciences and Nutrition, Karolinska Institutet, Hälsovägen 7, SE-141 83 Huddinge, Sweden.
Alexander D MacKerellDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, 20 Penn Street, Baltimore, MD 21201, USA.
Lennart NilssonDepartment of Biosciences and Nutrition, Karolinska Institutet, Hälsovägen 7, SE-141 83 Huddinge, Sweden. Electronic address: lennart.nilsson@ki.se.
Karolinska Institutet · SEUniversity of Maryland, Baltimore · US

Funding

Oligonucleotide Conformational HeterogeneityR01GM051501 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D · 2003 to 2018
$3.6M
Carbohydrate force fields for structure, dynamics and molecular recognitionR01GM070855 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D · 2005 to 2018
$3.5M
HALOGEN FREE ENERGY DATABASE FOR RATIONAL DRUG DESIGNR29GM051501 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI MACKERELL, ALEXANDER D. · 1996 to 2000
$108k
NIGMS NIH HHS R01 GM051501NIGMS NIH HHS R01 GM070855NIGMS NIH HHS R29 GM051501
6 · The paper itself

Abstract

Modified nucleotides are ubiquitous and important to tRNA structure and function. To understand their effect on tRNA conformation, we performed a series of molecular dynamics simulations on yeast tRNA

Indexed as

Escherichia coliHIVMagnesiumNucleic Acid ConformationRibonucleotidesRNA, TransferSaccharomyces cerevisiaeMagnesiumRibonucleotidesRNA, TransferMagnesiumModified nucleotideMolecular dynamicsNucleic acidsStructureTransfer RNA

Identifiers

PMID27364608
PMCPMC5052103
OpenAlexW2436892835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.