ReviewCurrent infectious disease reports2016
Abdominal Sepsis.
Review in Current infectious disease reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03163095 (Closed Versus Open Abdomen in the Surgical Treatment of Severe Secondary Peritonitis), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Closed Versus Open Abdomen in the Surgical Treatment of Severe Secondary Peritonitis: a Randomized Controlled Clinical Trial
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- The unrestricted global effort to complete the COOL trial.World journal of emergency surgery : WJES · 2023Trial
- Open or closed abdomen post laparotomy to control severe abdominal sepsis: a survival analysis.Revista do Colegio Brasileiro de Cirurgioes · 2024Article
- The Role of Abdominal Drain Cultures in Managing Abdominal Infections.Antibiotics (Basel, Switzerland) · 2022Review
- Current progress of source control in the management of intra-abdominal infections.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2020Review
- Intra- abdominal sepsis from a perforated duodenal ulcer-Management of a difficult surgical abdomen.International journal of surgery case reports · 2019Article
- Early Versus Delayed Source Control in Open Abdomen Management for Severe Intra-abdominal Infections: A Retrospective Analysis on 111 Cases.World journal of surgery · 2018Article
- What every intensivist should know about the management of peritonitis in the intensive care unit.Revista Brasileira de terapia intensiva · 2018Article
- Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial.World journal of emergency surgery : WJES · 2018Article
- Getting the invite list right: a discussion of sepsis severity scoring systems in severe complicated intra-abdominal sepsis and randomized trial inclusion criteria.World journal of emergency surgery : WJES · 2018Article
- Article
- Risk factors for excessively prolonged meropenem use in the intensive care setting: a case-contol study.BMC infectious diseases · 2017Article
- Open Abdomen Management andGastroenterology research and practice · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal infections are an important challenge for the intensive care physician. In an era of increasing antimicrobial resistance, selecting the appropriate regimen is important and, with new drugs coming to the market, correct use is important more than ever before and abdominal infections are an excellent target for antimicrobial stewardship programs. Biomarkers may be helpful, but their exact role in managing abdominal infections remains incompletely understood. Source control also remains an ongoing conundrum, and evidence is increasing that its importance supersedes the impact of antibiotic therapy. New strategies such as open abdomen management may offer added benefit in severely ill patients, but more data are needed to identify its exact role. The role of fungi and the need for antifungal coverage, on the other hand, have been investigated extensively in recent years, but at this point, it remains unclear who requires empirical as well as directed therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.