Evidence map›Paper›PMID 27363822›Full record

ArticleJournal of clinical pharmacy and therapeutics2016

A substudy evaluating treatment intensification on medication adherence among hypertensive patients receiving home blood pressure telemonitoring and pharmacist management.

P A Pawloski, S E Asche, N K Trower, A R Bergdall, S P Dehmer, M V Maciosek, R A Nyboer, P J O'Connor, J M Sperl-Hillen, B B Green and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of clinical pharmacy and therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00781365 (Home Blood Pressure Telemonitoring and Case Management to Control Hypertension), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00781365 nacompletednot on this map

Home Blood Pressure Telemonitoring and Case Management to Control Hypertension

TypeinterventionalSponsorHealthPartners InstituteRan2009 to 2012Enrolled450ConditionsHypertensionArmsTelemonitors and pharmacy management
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

P A PawloskiHealthPartners Institute, Minneapolis, MN, USA.
S E AscheHealthPartners Institute, Minneapolis, MN, USA.
N K TrowerHealthPartners Institute, Minneapolis, MN, USA.
A R BergdallHealthPartners Institute, Minneapolis, MN, USA.
S P DehmerHealthPartners Institute, Minneapolis, MN, USA.
M V MaciosekHealthPartners Institute, Minneapolis, MN, USA.
R A NyboerHealthPartners Institute, Minneapolis, MN, USA.
P J O'ConnorHealthPartners Institute, Minneapolis, MN, USA.
J M Sperl-HillenHealthPartners Institute, Minneapolis, MN, USA.
B B GreenGroup Health Research Institute, Seattle, WA, USA.
K L MargolisHealthPartners Institute, Minneapolis, MN, USA.

Funding

Home Blood Pressure Telemonitoring and Case Management to Control HypertensionR01HL090965 · NHLBI · HEALTHPARTNERS INSTITUTE · PI MARGOLIS, KAREN L · 2008 to 2015
$3.3M
NHLBI NIH HHS R01 HL090965
6 · The paper itself

Abstract

WHAT IS KNOWN AND

objectiveHypertension is a leading cause of death and major contributor to heart attacks, strokes, heart and kidney failure. Antihypertensive (HTN medication) non-adherence contributes to uncontrolled hypertension. Effective initiatives to improve uncontrolled hypertension include a team-based approach with home blood pressure (BP) monitoring. Our study objective was to evaluate whether objectively measured medication adherence was influenced by home BP telemonitoring and pharmacist management.

methodsWe analysed HTN medication adherence in 240 patients who received home BP telemonitoring and pharmacist intervention (TI). Adherence was measured based on prescription fills and the proportion of days covered (PDC). HTN medications continued pre- to post-baseline were similar for telemonitoring intervention (TI) and usual care (UC) patients (rate ratio = 1·00, P = 0·90). RESULTS AND DISCUSSION: More HTN medications were discontinued pre- to post-baseline in TI patients (rate ratio = 1·38, P = 0·04). Similarly, more HTN medications were added in TI patients (rate ratio = 2·46, P < 0·001). The proportion with a mean PDC ≥ 0·8 for HTN medications added after baseline and overall adherence did not differ between groups. WHAT IS NEW AND

conclusionMedication adherence was high in both groups; however, medication adherence was not significantly altered by the intervention. There were more medication modifications and greater medication intensification among TI patients.

Indexed as

Drug MonitoringAgedAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleHumansHypertensionMaleMiddle AgedPharmacistsAntihypertensive Agentsadherenceantihypertensiveclinical pharmacydisease managementhypertension

Identifiers

PMID27363822
PMCPMC5644343

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.