Evidence map›Paper›PMID 27362844›Full record

ArticlePloS one2016

25-Hydroxyvitamin D and Parathyroid Hormone Levels Are Independently Associated with the Hemoglobin A1c Level of Korean Type 2 Diabetic Patients: The Dong-Gu Study.

Seong-Woo Choi, Sun-Seog Kweon, Young-Hoon Lee, So-Yeon Ryu, Jin-Su Choi, Jung-Ae Rhee, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, Hee Nam Kim and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Seong-Woo ChoiDepartment of Preventive Medicine, Chosun University Medical School, 309, Pilmun-daero, Dong-gu, Gwangju 501-759, Republic of Korea.ORCID http://orcid.org/0000-0002-6150-3934
Sun-Seog KweonDepartment of Preventive Medicine, Chonnam National University Medical School, 160, Baekseo-ro, Dong-gu, Gwangju 501-746, Republic of Korea.
Young-Hoon LeeDepartment of Preventive Medicine & Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, 344-2 Shinyong-dong, Iksan, Jeollabukdo 570-711, Republic of Korea.
So-Yeon RyuDepartment of Preventive Medicine, Chosun University Medical School, 309, Pilmun-daero, Dong-gu, Gwangju 501-759, Republic of Korea.
Jin-Su ChoiDepartment of Preventive Medicine, Chonnam National University Medical School, 160, Baekseo-ro, Dong-gu, Gwangju 501-746, Republic of Korea.
Jung-Ae RheeDepartment of Preventive Medicine, Chonnam National University Medical School, 160, Baekseo-ro, Dong-gu, Gwangju 501-746, Republic of Korea.
Hae-Sung NamDepartment of Preventive Medicine, Chungnam National University Medical School, Munhwa 1(il)-dong, Jung-gu, Daejeon 301-747, Republic of Korea.
Seul-Ki JeongDepartment of Neurology & Research Institute of Clinical Medicine, Biomedical Institute of Chonbuk National University Hospital, Chonbuk National University, San 2-20, Geumam-dong, Deokjin-gu, Jeonju, Jeollabukdo 561-180, Republic of Korea.
Kyeong-Soo ParkDepartment of Preventive Medicine, Seonam University College of Medicine, 439, Chunhyang-ro, Namwon, Jeollabukdo 590-711, Republic of Korea.
Hee Nam KimCenter for Creative Biomedical Scientists, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea.
Min-Ho ShinDepartment of Preventive Medicine, Chonnam National University Medical School, 160, Baekseo-ro, Dong-gu, Gwangju 501-746, Republic of Korea.
Chonnam National University · KRChosun University · KRChungnam National University · KRJeonbuk National University Hospital · KRSeonam University · KRWonkwang University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In type 2 diabetic patients, the relationships between 25-hydroxyvitamin D and parathyroid hormone levels, and glycemic control, remain unclear. We evaluated associations between 25-hydroxyvitamin D, parathyroid hormone, and hemoglobin A1c levels after adjusting for other covariates, including log transformed 25-hydroxyvitamin D levels and log transformed parathyroid hormone levels, in Korean patients with type 2 diabetes. In total, 1,175 patients with type 2 diabetes were selected from 8,857 individuals who completed the baseline survey of the Dong-gu study, conducted in Korea from 2007 to 2010. After adjusting for other covariates, we found that the mean hemoglobin A1c level was inversely associated with the 25-hydroxyvitamin D level (Q1: 7.47% [7.30-7.63], Q2: 7.25% [7.09-7.40], Q3: 7.17% [7.02-7.32], Q4: 7.19% [7.02-7.35]; p for trend = 0.021, p for between groups = 0.050) and the parathyroid hormone level (Q1: 7.35% [7.19-7.51], Q2: 7.34% [7.19-7.50], Q3: 7.28% [7.13-7.43], Q4: 7.09% [6.94-7.24]; p for trend = 0.022, p for between groups = 0.048). However, the mean fasting glucose level was not associated with either the 25-hydroxyvitamin D or parathyroid hormone level. In conclusion, inverse associations were evident between hemoglobin A1c, 25-hydroxyvitamin D and parathyroid hormone levels in Korean patients with type 2 diabetes. The associations remained significant after adjusting for other covariates, including the log transformed 25-hydroxyvitamin D levels and log transformed parathyroid hormone levels.

Indexed as

AgedBlood GlucoseDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHealth SurveysHumansMaleMiddle AgedParathyroid HormoneProspective StudiesRepublic of KoreaVitamin D25-hydroxyvitamin DBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanParathyroid HormoneVitamin D

Identifiers

PMID27362844
PMCPMC4928954
OpenAlexW2471030162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.