ArticlePloS one2016
Air Pollution and Subtypes, Severity and Vulnerability to Ischemic Stroke-A Population Based Case-Crossover Study.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 40 citations in OpenAlex.
- Long-term exposure to fine particulate matter constituents and incident stroke risk among middle-aged and older adults in China: a cohort study.Frontiers in public health · 2026Article
- Attributable risk of hospital admissions for ischemic stroke due to ambient air pollution: a time-series study in Zhangzhou, China.Frontiers in public health · 2026Article
- Impact of air pollution and noise exposure on cardiovascular disease incidence and mortality: A systematic review.Heliyon · 2024Review
- Emerging Stroke Risk Factors: A Focus on Infectious and Environmental Determinants.Journal of cardiovascular development and disease · 2024Review
- Time-Series analysis of short-term exposure to air pollutants and daily hospital admissions for stroke in Tabriz, Iran.PloS one · 2024Article
- Long-term air pollution exposure and incident stroke in American older adults: A national cohort study.Global epidemiology · 2022Article
- Effect of ambient temperature and other environmental factors on stroke emergency department visits in Beijing: A distributed lag non-linear model.Frontiers in public health · 2022Article
- Association of short-term exposure to sulfur dioxide and hospitalization for ischemic and hemorrhagic stroke in Guangzhou, China.BMC public health · 2020Article
- Association between ambient fine particulate pollution and hospital admissions for cause specific cardiovascular disease: time series study in 184 major Chinese cities.BMJ (Clinical research ed.) · 2019Article
- Case-crossover analysis of short-term particulate matter exposures and stroke in the health professionals follow-up study.Environment international · 2019Article
- Synergism of Short-Term Air Pollution Exposures and Neighborhood Disadvantage on Initial Stroke Severity.Stroke · 2017Article
- The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study.Environmental health : a global access science source · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
background and purposeFew studies have examined the association between air pollutants and ischemic stroke subtypes. We examined acute effects of outdoor air pollutants (PM10, NO2, O3, CO, SO2) on subtypes and severity of incident ischemic stroke and investigated if pre-existing risk factors increased susceptibility.
methodsWe used a time stratified case-crossover study and stroke cases from the South London Stroke Register set up to capture all incident cases of first ever stroke occurring amongst residents in a geographically defined area. The Oxford clinical and TOAST etiological classifications were used to classify subtypes. A pragmatic clinical classification system was used to assess severity. Air pollution concentrations from the nearest background air pollution monitoring stations to patients' residential postcode centroids were used. Lags from 0 to 6 days were investigated.
resultsThere were 2590 incident cases of ischemic stroke (1995-2006). While there were associations at various lag times with several pollutants, overall, there was no consistent pattern between exposure and risk of ischemic stroke subtypes or severity. The possible exception was the association between NO2 exposure and small vessel disease stroke-adjusted odds ratio of 1.51 (1.12-2.02) associated with an inter-quartile range increase in the lag 0-6 day average for NO2. There were no clear associations in relation to pre-existing risk factors.
conclusionsOverall, we found little consistent evidence of association between air pollutants and ischemic stroke subtypes and severity. There was however a suggestion that increasing NO2 exposure might be associated with higher risk of stroke caused by cerebrovascular small vessel disease.
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