Evidence map›Paper›PMID 27362512›Full record

ArticleNursing research

Sleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure: A Mediation Analysis.

Sangchoon Jeon, Nancy S Redeker

Registry-linked trialAbstract read
In one paragraph

Article in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05366673 (Effect of Massage Therapy on Fatigue and Sleep Quality in Patients With Heart Failure in Intensive Care Unit), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05366673 nacompletednot on this map

Effect of Massage Therapy on Fatigue and Sleep Quality in Patients With Heart Failure in Intensive Care Unit

TypeinterventionalSponsorNational Yang Ming Chiao Tung UniversityRan2021 to 2022Enrolled106ConditionsMassage, Heart FailureArmsmassage
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sangchoon JeonSangchoon Jeon, PhD, is Research Scientist, Yale School of Nursing, West Haven, Connecticut. Nancy S. Redeker, PhD, RN, FAHA, FAAN, is Beatrice Renfield Term Professor of Nursing, Yale School of Nursing, West Haven, Connecticut.
Nancy S Redeker

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Sleep and Functional Performance in Heart FailureR01NR008022 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S · 2003 to 2006
$1.7M
Yale Center for Sleep Disturbance in Acute and Chronic ConditionsP20NR014126 · NINR · YALE UNIVERSITY · PI REDEKER, NANCY S, YAGGI, HENRY KLAR · 2012 to 2016
$1.4M
NCATS NIH HHS UL1 TR001863NINR NIH HHS P20 NR014126NINR NIH HHS R01 NR008022
6 · The paper itself

Abstract

backgroundSleep disturbance is common among patients with heart failure (HF) who also experience symptom burden and poor functional performance.

objectiveWe evaluated the extent to which sleep-related, daytime symptoms (fatigue, excessive daytime sleepiness, and depressive symptoms) mediate the relationship between sleep disturbance and functional performance among patients with stable HF.

methodsWe recruited patients with stable HF for this secondary analysis of data from a cross-sectional, observational study. Participants completed unattended ambulatory polysomnography from which the Respiratory Disturbance Index was calculated, along with a Six-Minute Walk Test, questionnaires to elicit sleep disturbance (Pittsburgh Sleep Quality Index, Insomnia Symptoms from the Sleep Habits Questionnaire), daytime symptoms (Center for Epidemiologic Studies Depression Scale, Global Fatigue Index, Epworth Sleepiness Scale), and self-reported functional performance (Medical Outcomes Study SF36 V2 Physical Function Scale). We used structural equation modeling with latent variables for the key analysis. Follow-up, exploratory regression analysis with bootstrapped samples was used to examine the extent to which individual daytime symptoms mediated effects of sleep disturbance on functional performance after controlling for clinical and demographic covariates.

resultsThe sample included 173 New York Heart Association Class I-IV HF patients (n = 60/34.7% women; M = 60.7, SD = 16.07 years of age). Daytime symptoms mediated the relationship between sleep disturbance and functional performance. Fatigue and depression mediated the relationship between insomnia symptoms and self-reported functional performance, whereas fatigue and sleepiness mediated the relationship between sleep quality and functional performance. Sleepiness mediated the relationship between the respiratory index and self-reported functional performance only in people who did not report insomnia.

conclusionsDaytime symptoms explain the relationships between sleep disturbance and functional performance in stable HF.

Indexed as

Activities of Daily LivingSelf DisclosureSeverity of Illness IndexAdultAgedCircadian RhythmFemaleHeart FailureHumansMaleMiddle AgedRisk FactorsSleep Wake DisordersSurveys and Questionnaires

Identifiers

PMID27362512
PMCPMC4930009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.