Evidence map›Paper›PMID 27358900›Full record

ArticleStem cell investigation2016

Acute promyelocytic leukemia co-existing with JAK2 V617F positive myeloproliferative neoplasm: a case report.

Aleksandra Mamorska-Dyga, Jingjing Wu, Pallavi Khattar, Faisal M H Ronny, Humayun Islam, Karen Seiter, Delong Liu

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Acute promyelocyte leukemia arose fromLeukemia research reports · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Aleksandra Mamorska-Dyga1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Jingjing Wu1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Pallavi Khattar1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Faisal M H Ronny1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Humayun Islam1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Karen Seiter1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
Delong Liu1 Department of Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA ; 2 Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China ; 3 Department of Pathology, Westchester Medical Center and New York Medical College, Valhalla, NY 10595, USA.
First Affiliated Hospital of Zhengzhou University · CNWestchester Medical Center · USNew York Medical College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The V617F mutation of Janus-associated kinase 2 (JAK2) is commonly seen in myeloproliferative neoplasms (MPN). Transformation of JAK2 positive MPNs to acute leukemia has been reported. We here report a case of acute promyelocytic leukemia which was later confirmed to have a co-existing JAK2 V617F positive MPN. In addition, the patient was found to have FLT3-TKD mutation, which, together with PML/RARa, could play a role in the MPN transformation to APL.

Indexed as

Acute myelogenous leukemia (APL)Janus-associated kinase 2 (JAK2)myeloproliferative neoplasms (MPN)PML/RARa

Identifiers

PMID27358900
PMCPMC4923643
OpenAlexW2326557601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.