ArticleClinical and experimental reproductive medicine2016
A retrospective study of single frozen-thawed blastocyst transfer.
Article in Clinical and experimental reproductive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Aneuploidy rates and clinical outcomes in vitrified-warmed blastocyst transfer cycles: comparison of biopsy at fresh blastocyst versus vitrified-warmed blastocyst.Clinical and experimental reproductive medicine · 2026Article
- Comparative Outcomes of Day 3 and Day 5 Frozen-Thawed Embryo Transfers: A Retrospective Clinical Study.Biomedicines · 2025Article
- Clinical outcomes of preimplantation genetic testing for aneuploidy in high-risk patients: a retrospective cohort study.Clinical and experimental reproductive medicine · 2024Article
- Laser-assisted hatching on clinical and neonatal outcomes in patients undergoing single vitrified Blastocyst transfer: A propensity score-matched study.Reproductive medicine and biology · 2021Article
- Does the sex ratio of singleton births after frozen single blastocyst transfer differ in relation to blastocyst development?Reproductive biology and endocrinology : RB&E · 2020Article
- Associations of post-warming embryo or blastocyst development with clinical pregnancy in vitrified embryo or blastocyst transfer cycles.Clinical and experimental reproductive medicine · 2020Article
- Cell number considerations for blastocyst transfer in younger patients.Journal of assisted reproduction and genetics · 2020Article
- Retrospective study of single vitrified-warmed blastocyst transfer cycles according to the presence of morphokinetic variables.Clinical and experimental reproductive medicine · 2018Article
- Pregnancy rates for single embryo transfer (SET) of day 5 and day 6 blastocysts after cryopreservation by vitrification and slow freeze.Journal of assisted reproduction and genetics · 2017Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the clinical outcomes of single frozen-thawed blastocyst transfer cycles according to the hatching status of frozen-thawed blastocysts.
methodsFrozen-thawed blastocysts were divided into three groups according to their hatching status as follows: less-than-expanded blastocyst (≤EdB), hatching blastocyst (HgB), and hatched blastocyst (HdB). The female age and infertility factors of each group were evaluated. The quality of the single frozen-thawed blastocyst was also graded as grade A, tightly packed inner cell mass (ICM) and many cells organized in the trophectoderm epithelium (TE); grade B, several and loose ICM and TE; and grade C, very few ICM and a few cells in the TE. The clinical pregnancy and implantation rate were compared between each group. The data were analyzed by either t-test or chi-square analysis.
resultsThere were no statistically significant differences in average female ages, infertility factors, or the distribution of blastocyst grades A, B, and C in each group. There was no significant difference in the clinical pregnancy and implantation rate of each group according to their blastocyst grade. However, there was a significant difference in the clinical pregnancy and implantation rate between each group. In the HdB group, the clinical pregnancy and implantation rate were similar regardless of the blastocyst quality.
conclusionThere was an effect on the clinical outcomes depending on whether the blastocyst hatched during single frozen-thawed blastocyst transfer. When performing single frozen-thawed blastocyst transfer, the hatching status of the frozen-thawed blastocyst may be a more important parameter for clinical outcomes than the quality of the frozen-thawed blastocyst.
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