ArticlePublic health action2016
Two methods for setting child-focused tuberculosis care targets.
Article in Public health action, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis.Lancet (London, England) · 2020Pooled it
- Where are the missing people affected by tuberculosis? A programme review of patient-pathway and cascade of care to optimise tuberculosis case-finding, treatment and prevention in Cambodia.BMJ global health · 2023Article
- Tuberculosis Infection in Children and Adolescents.Pathogens (Basel, Switzerland) · 2022Review
- Addressing the Data Gaps on Child and Adolescent Tuberculosis.Pathogens (Basel, Switzerland) · 2022Review
- Feasibility of a randomized clinical trial evaluating a community intervention for household tuberculosis child contact management in Cameroon and Uganda.Pilot and feasibility studies · 2022Article
- Estimating the population at high risk for tuberculosis through household exposure in high-incidence countries: a model-based analysis.EClinicalMedicine · 2021Article
- Article
- Cost-effectiveness of scaling up short course preventive therapy for tuberculosis among children across 12 countries.EClinicalMedicine · 2021Article
- One size does not fit all: preventing tuberculosis among child contacts.BMJ global health · 2019Article
- Potential effect of household contact management on childhood tuberculosis: a mathematical modelling study.The Lancet. Global health · 2018Article
- Latent tuberculosis infection and tuberculosis in children and adolescents.Einstein (Sao Paulo, Brazil) · 2018Article
- The burden of multidrug-resistant tuberculosis in children.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Review
- Effectiveness of WHO's pragmatic screening algorithm for child contacts of tuberculosis cases in resource-constrained settings: a prospective cohort study in Uganda.The Lancet. Respiratory medicine · 2018Article
- Prospective Observational Study of Incidence and Preventable Burden of Childhood Tuberculosis, Kenya.Emerging infectious diseases · 2018Observational
- The global burden of tuberculosis mortality in children: a mathematical modelling study.The Lancet. Global health · 2017Article
- Knowing how many children to find is the first step in finding them.Public health action · 2016Article
- Global Burden of Childhood Tuberculosis.Pneumonia (Nathan Qld.) · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo allocate resources for household contact investigations, tuberculosis (TB) programs need estimates of the numbers of child contacts requiring care.
designWe developed two methods to estimate annual numbers of child contacts aged 0-14 years requiring evaluation and treatment. Method 1 combines local data using simple formulas. Using publicly available data, Method 2 uses a linear regression model based on Demographic and Health Survey and World Bank data to estimate the number of children per household, then combines these results with case notifications and risk estimates of disease and infection.
resultsApplying Method 1 to data from Malawi indicated that every year ~21 000 child contacts require evaluation and ~1900 should be diagnosed with TB. Applying Method 2 to all countries suggested that, globally, 2.41 million (95% uncertainty interval [UI] 2.36-2.46) children aged <5 years, and 5.07 million (95%UI 4.81-5.34) children aged 5-14 years live in households of adult patients with known TB. Of these, 239 014 (95%UI 118 649-478581) and 419 816 (95%UI 140600-1 268805), respectively, will have TB. An additional 848 453 (95%UI 705838-1 017551) and 2660 885 (95%UI 2080517-3 413 189), respectively, will be infected.
conclusionIt is feasible to use available data to set programmatic evaluation and treatment targets to improve care for child contacts of patients with TB.
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