Evidence map›Paper›PMID 27358784›Full record

ArticleWorld journal of transplantation2016

Ventilator associated pneumonia following liver transplantation: Etiology, risk factors and outcome.

Antonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Nava, Pierluigi Viale, Stefano Faenza

Open access · hybridAbstract read
In one paragraph

Article in World journal of transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Pneumonia after Solid Organ Transplantation.Seminars in respiratory and critical care medicine · 2026
    Review
  3. Article
  4. Review
  5. A nationwide retrospective analysis of ventilator-associated pneumonia in the US.Proceedings (Baylor University. Medical Center) · 2022
    Article
  6. Article
  7. Risk Factors for Mortality Due to Ventilator-Associated Pneumonia in a Chinese Hospital: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  8. Article
  9. The Epidemiology and Risk Factors for Postoperative Pneumonia.Journal of clinical medicine research · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antonio SiniscalchiAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Lucia AuriniAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Beatrice BeniniAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Lorenzo GamberiniAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Stefano NavaAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Pierluigi VialeAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Stefano FaenzaAntonio Siniscalchi, Lucia Aurini, Beatrice Benini, Lorenzo Gamberini, Stefano Faenza, Division of Anesthesiology, Department of General Surgery of Sant'Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the incidence, etiology, risk factors and outcome of ventilator-associated pneumonia (VAP) in patients undergoing orthotopic liver transplantation (OLT).

methodsThis retrospective study considered 242 patients undergoing deceased donor OLT. VAP was diagnosed according to clinical and microbiological criteria.

resultsVAP occurred in 18 (7.4%) patients, with an incidence of 10 per 1000 d of mechanical ventilation (MV). Isolated bacterial etiologic agents were mainly Enterobacteriaceae (79%). Univariate logistic analysis showed that model for end-stage liver disease (MELD) score, pre-operative hospitalization, treatment with terlipressin, Child-Turcotte-Pugh score, days of MV and red cell transfusion were risk factors for VAP. Multivariate analysis, considering significant risk factors in univariate analysis, demonstrated that pneumonia was strongly associated with terlipressin usage, pre-operative hospitalization, days of MV and red cell transfusion. Mortality rate was 22% in the VAP group vs 4% in the group without VAP.

conclusionOur data suggest that VAP is an important cause of nosocomial infection during postoperative period in OLT patients. MELD score was a significant risk factor in univariate analysis. Multiple transfusions, treatment with terlipressin, preoperative hospitalization rather than called to the hospital while at home and days of MV constitute important risk factors for VAP development.

Indexed as

InfectionLiver transplantationPerioperative periodVentilator associated pneumonia

Identifiers

PMID27358784
PMCPMC4919743
OpenAlexW2473342491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.