Evidence map›Paper›PMID 27358673›Full record

ReviewWorld journal of gastrointestinal surgery2016

Parenchymal-sparing liver surgery in patients with colorectal carcinoma liver metastases.

Fernando A Alvarez, Rodrigo Sanchez Claria, Sebastian Oggero, Eduardo de Santibañes

Abstract readReview
In one paragraph

Review in World journal of gastrointestinal surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Laparoscopic Parenchymal-Sparing Hepatectomy: the New Maximally Minimal Invasive Surgery of the Liver-a Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Pooled it
  3. Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Pooled it
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  19. Treatment of colon cancer with multiple liver metastases.Proceedings (Baylor University. Medical Center) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fernando A AlvarezFernando A Alvarez, Rodrigo Sanchez Claria, Sebastian Oggero, Eduardo de Santibañes, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires C1181ACH, Argentina.
Rodrigo Sanchez ClariaFernando A Alvarez, Rodrigo Sanchez Claria, Sebastian Oggero, Eduardo de Santibañes, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires C1181ACH, Argentina.
Sebastian OggeroFernando A Alvarez, Rodrigo Sanchez Claria, Sebastian Oggero, Eduardo de Santibañes, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires C1181ACH, Argentina.
Eduardo de SantibañesFernando A Alvarez, Rodrigo Sanchez Claria, Sebastian Oggero, Eduardo de Santibañes, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires C1181ACH, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver resection is the treatment of choice for patients with colorectal liver metastases (CLM). However, major resections are often required to achieve R0 resection, which are associated with substantial rates of morbidity and mortality. Maximizing the amount of residual liver gained increasing significance in modern liver surgery due to the high incidence of chemotherapy-associated parenchymal injury. This fact, along with the progressive expansion of resectability criteria, has led to the development of a surgical philosophy known as "parenchymal-sparing liver surgery" (PSLS). This philosophy includes a variety of resection strategies, either performed alone or in combination with ablative therapies. A profound knowledge of liver anatomy and expert intraoperative ultrasound skills are required to perform PSLS appropriately and safely. There is a clear trend toward PSLS in hepatobiliary centers worldwide as current evidence indicates that tumor biology is the most important predictor of intrahepatic recurrence and survival, rather than the extent of a negative resection margin. Tumor removal avoiding the unnecessary sacrifice of functional parenchyma has been associated with less surgical stress, fewer postoperative complications, uncompromised cancer-related outcomes and higher feasibility of future resections. The increasing evidence supporting PSLS prompts its consideration as the gold-standard surgical approach for CLM.

Indexed as

Ablative therapiesColorectal liver metastasesComplicationsLiver failureParenchymal-sparing hepatectomyResection marginsUltrasound

Identifiers

PMID27358673
PMCPMC4919708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.