Evidence map›Paper›PMID 27358563›Full record

ArticleInternational journal of nanomedicine2016

Symbiosis theory-directed green synthesis of silver nanoparticles and their application in infected wound healing.

Lu Wen, Pei Zeng, Liping Zhang, Wenli Huang, Hui Wang, Gang Chen

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Assessing Genetic Diversity in Endangered PlantInternational journal of molecular sciences · 2024
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Biocidal Activity of Metal Nanoparticles Synthesized byJournal of microbiology and biotechnology · 2020
    Article
  10. Functionalized Gold and Silver Bimetallic Nanoparticles UsingInternational journal of nanomedicine · 2020
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lu WenDepartment of Pharmaceutics, School of Pharmacy, Guangzhou, People's Republic of China.
Pei ZengDepartment of Pharmaceutics, School of Pharmacy, Guangzhou, People's Republic of China.
Liping ZhangDepartment of Pharmaceutics, School of Pharmacy, Guangzhou, People's Republic of China.
Wenli HuangDepartment of Pharmaceutics, School of Pharmacy, Guangzhou, People's Republic of China.
Hui WangSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, People's Republic of China.
Gang ChenDepartment of Pharmaceutics, School of Pharmacy, Guangzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, silver nanoparticles (AgNPs) were synthesized for the first time using an antibacterial endophytic fungus of Chinese medicinal herb Orchidantha chinensis, which has anti-inflammatory and antimicrobial activities. The AgNPs were analyzed by various characterization techniques to reveal their morphology, chemical composition, and stability. Also, the relationship between Chinese medicinal herbs, endophytic fungi, and the property of AgNPs was investigated for the first time. Interestingly, an experiment performed in this study revealed the proteins produced by the endophytic fungus to be capped on the nanoparticles, which led to an increase in the stability of spherical and polydispersed AgNPs with low aggregation for over 6 months. More importantly, further study demonstrated that the AgNPs possessed superior antibacterial activity and effectively promoted wound healing. Altogether, the biosynthesis of active AgNPs using the endophytic fungus from Chinese medicinal herb based on the symbiosis theory is simple, eco-friendly, and promising.

Indexed as

AnimalsAnti-Bacterial AgentsColony Count, MicrobialCytokinesDynamic Light ScatteringGreen Chemistry TechnologyHydroxyprolineInflammationMetal NanoparticlesNanomedicinePseudomonas aeruginosaRatsRats, Sprague-DawleySilverSkinSpectrophotometry, UltravioletAnti-Bacterial AgentsCytokinesHydroxyprolineSilverendophytic fungiOrchidantha chinensissilver nanoparticlessymbiosis theorywound healing

Identifiers

PMID27358563
PMCPMC4912321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.