ArticleProceedings. Biological sciences2016
Cellular and molecular remodelling of a host cell for vertical transmission of bacterial symbionts.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 77 citations in OpenAlex.
- A transcription factor regulates development of a bacteria-housing eukaryotic cell through DNA damage mitigation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Cellular remodeling of ovarian follicular epithelial cells transmits an obligate nutritional endosymbiont in a scale insect.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Fidelity in co-diversified symbiosis.Nature communications · 2026Article
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- Ecological drift during colonization drives within-host and between-host heterogeneity in an animal-associated symbiont.PLoS biology · 2024Article
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- Extracellular symbiont colonizes insect during embryo development.ISME communications · 2024Article
- Effects of developmental stages, sex difference, and diet types of the host marmalade hoverfly (Frontiers in microbiology · 2024Article
- Comparative Genomics Reveals Three Genetic Groups of the Whitefly Obligate EndosymbiontInsects · 2023Article
- The Improvement of Fluorescence In Situ Hybridization Technique Based on Explorations of Symbionts in Cicadas.International journal of molecular sciences · 2023Article
- Two Distinct Genotypes ofInsects · 2023Article
- The Dynamic Distribution ofInsects · 2023Article
- Article
- Subcellular Niche Segregation of Co-Obligate Symbionts in Whiteflies.Microbiology spectrum · 2023Article
- Editorial: Diversity of beetles and associated microorganisms.Frontiers in microbiology · 2023Article
- For the road: calibrated maternal investment in light of extracellular symbiont transmission.Proceedings. Biological sciences · 2022Article
- Autophagy Regulates Whitefly-Symbiont Metabolic Interactions.Applied and environmental microbiology · 2022Article
- Morphological adaptation for ectosymbiont maintenance and transmission during metamorphosis inFrontiers in physiology · 2022Article
- Whitefly endosymbionts: IPM opportunity or tilting at windmills?Journal of pest science · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Various insects require intracellular bacteria that are restricted to specialized cells (bacteriocytes) and are transmitted vertically via the female ovary, but the transmission mechanisms are obscure. We hypothesized that, in the whitefly Bemisia tabaci, where intact bacteriocytes (and not isolated bacteria) are transferred to oocytes, the transmission mechanism would be evident as cellular and molecular differences between the nymph (pre-adult) and adult bacteriocytes. We demonstrate dramatic remodelling of bacteriocytes at the developmental transition from nymph to adulthood. This transition involves the loss of cell-cell adhesion, high division rates to constant cell size and onset of cell mobility, enabling the bacteriocytes to crawl to the ovaries. These changes are accompanied by cytoskeleton reorganization and changes in gene expression: genes functioning in cell-cell adhesion display reduced expression and genes involved in cell division, cell motility and endocytosis/exocytosis have elevated expression in adult bacteriocytes, relative to nymph bacteriocytes. This study demonstrates, for the first time, how developmentally orchestrated remodelling of gene expression and correlated changes in cell behaviour underpin the capacity of bacteriocytes to mediate the vertical transmission and persistence of the symbiotic bacteria on which the insect host depends.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.