ArticleAmerican journal of epidemiology2016
High Maternal Body Mass Index in Early Pregnancy and Risks of Stillbirth and Infant Mortality-A Population-Based Sibling Study in Sweden.
Article in American journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 29 citations in OpenAlex.
- Prolonged pregnancy and stillbirth among women with overweight or obesity - a population-based study in Sweden including 64,632 women.BMC pregnancy and childbirth · 2023Trial
- Grandmaternal body mass index in early pregnancy and risk of infant mortality in grandoffspring: a population-based multigeneration cohort study.The American journal of clinical nutrition · 2024Article
- Grandmaternal body mass index in early pregnancy and risk of grandoffspring stillbirth: a nationwide, 3-generation cohort study.American journal of epidemiology · 2024Article
- Maternal Prepregnancy Obesity Affects Foetal Growth, Birth Outcome, Mode of Delivery, and Miscarriage Rate in Austrian Women.International journal of environmental research and public health · 2023Article
- Article
- Male Rat Offspring Are More Impacted by Maternal Obesity Induced by Cafeteria Diet than Females-Additive Effect of Postweaning Diet.International journal of molecular sciences · 2022Article
- Determinants for Perinatal Mortality in South China: A Prospective Cohort Study.Frontiers in pediatrics · 2022Article
- Findings in Stillbirths Associated with Placental Disease.American journal of perinatology · 2020Article
- Invited Commentary: The Causal Association Between Obesity and Stillbirth-Strengths and Limitations of the Consecutive-Pregnancies Approach.American journal of epidemiology · 2019Article
- Community-and proximate-level factors associated with perinatal mortality in Nigeria: evidence from a nationwide household survey.BMC public health · 2019Article
- Retrospective analysis of risk factors for low 1-minute Apgar scores in term neonates.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Understanding the consumption of folic acid during preconception, among Pakistani, Bangladeshi and white British mothers in Luton, UK: a qualitative study.BMC pregnancy and childbirth · 2018Article
- The Risks Associated With Obesity in Pregnancy.Deutsches Arzteblatt international · 2018Review
- Promoting healthy lifestyle in fertility clinics; an Australian perspective.Human reproduction open · 2018Article
- Gestational diabetes mellitus and interpregnancy weight change: A population-based cohort study.PLoS medicine · 2017Article
- Optimal timing for elective caesarean delivery in a Chinese population: a large hospital-based retrospective cohort study in Shanghai.BMJ open · 2017Article
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5 authors.
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Abstract
In a population-based case-control study, we investigated whether familial confounding influenced the associations between maternal overweight/obesity and risks of stillbirth and infant mortality by including both population and sister controls. Using nationwide data from the Swedish Medical Birth Register (1992-2011), we included all primiparous women with singleton births who also had a sister with a first birth during that time period. We used logistic regression analyses to calculate odds ratios (and 95% confidence intervals) adjusted for maternal age, height, smoking habits, education, and time period (5-year groups) of child's birth. Body mass index (BMI) was calculated as weight (kg)/height (m)(2) Compared with population controls with a normal BMI (18.5-24.9), stillbirth risk increased with increasing BMI (BMI 25-29.9: odds ratio (OR) = 1.51 (95% confidence interval (CI): 1.21, 1.89); BMI 30-34.9: OR = 1.77 (95% CI: 1.24, 2.50); BMI ≥35: OR = 3.16 (95% CI: 2.10, 4.76)). The sister case-control analyses revealed similar results. Offspring of obese women (BMI ≥30) had an increased risk of infant mortality when population controls were used (OR = 2.41, 95% CI: 1.83, 3.16), and an even higher risk was obtained when sister controls were used (OR = 4.04, 95% CI: 2.25, 7.25). We conclude that obesity in early pregnancy is associated with increased risks of stillbirth and infant mortality independently of genetic and early environmental risk factors shared within families.
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