Evidence map›Paper›PMID 27357597›Full record

ArticleBMC veterinary research2016

Evidence of Aujeszky's disease in wild boar in Serbia.

V Milicevic, S Radojicic, M Valcic, V Ivovic, V Radosavljevic

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  14. Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

V MilicevicVirology department, Institute of Veterinary Medicine of Serbia, Vojvode Toze 14, 11000, Belgrade, Serbia. mvekac@yahoo.com.
S RadojicicInfectious Animals Diseases and Diseases of Bees, Faculty of Veterinary Medicine, Bulevar oslobodjenja 18, 11000, Belgrade, Serbia.
M ValcicInfectious Animals Diseases and Diseases of Bees, Faculty of Veterinary Medicine, Bulevar oslobodjenja 18, 11000, Belgrade, Serbia.
V IvovicDepartment of Biodiversity, University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Glagoljaska 8, SI-6000, Koper, Slovenia.
V RadosavljevicInstitute of Veterinary Medicine of Serbia, Vojvode Toze 14, 11000, Belgrade, Serbia.
University of Primorska · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAujeszky's disease is a viral disease of suids caused by Suid Herpesvirus 1. The disease has worldwide distribution with significant economic impact. In Serbia, there is neither an Aujeszky's disease eradication nor national vaccination programme of domestic pigs. Since clinical symptoms of Aujeszky's disease are not specific, it is important to establish a link between clinical signs and presence of ADV active infection in wild boars. The aim of this study was to investigate the possibility of active infection within wild boar showing signs of ADV and also to examine relationship between isolates from domestic pigs and wild boar. Having in mind that virus has not been previously isolated from wild boars in Serbia, we report the first isolation of Suid Herpesvirus 1 from this species in Serbia.

resultsTissue and serum samples from 40 wild boars from eastern Serbia were examined for evidence of Aujeszky's disease (AD). Suid Herpesvirus 1 (SHV1), the cause of AD was isolated on PK15 cell line from three tissue samples, inducing cytopathic effect (CPE) with syncytia forming, and viral genome was detected by polymerase chain reaction (PCR) in eight samples. Genetic analysis of us4, us9 and ul49.5 partial sequences showed high homology between ADV isolates from wild boars and between isolates from wild boars and domestic animals. Neutralizing antibodies were not detected by virus neutralisation test (VNT) in sera from four out of eight PCR positive wild boars suggesting recent infection in those animals.

conclusionsThis is the first demonstration of Aujeszky's disease virus (ADV) in the wild boar population in Serbia although seroconversion has been detected previously.

Indexed as

AnimalsAntibodies, NeutralizingCell LineDNA, ViralFemaleHerpesvirus 1, SuidMalePolymerase Chain ReactionPseudorabiesSequence Homology, Nucleic AcidSerbiaSus scrofaSwineSwine DiseasesAntibodies, NeutralizingDNA, ViralAujeszky’s disease virusPCRVirus isolationVirus neutralization testWild boar

Identifiers

PMID27357597
PMCPMC4928280
OpenAlexW2471139230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.