Evidence map›Paper›PMID 27357425›Full record

ArticleJournal of human genetics2016

Nationwide survey for current clinical status of amniocentesis and maternal serum marker test in Japan.

Hidehiko Miyake, Shigehito Yamada, Yosuke Fujii, Hideaki Sawai, Naoko Arimori, Yasuko Yamanouchi, Yuka Ozasa, Makoto Kanai, Haruhiko Sago, Akihiko Sekizawa and 5 more

Erratum issuedAbstract read
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In one paragraph

Article in Journal of human genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The composition and capacity of the clinical genetics workforce in high-income countries: a scoping review.Genetics in medicine : official journal of the American College of Medical Genetics · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Hidehiko MiyakeClinical Genetics Unit, Kyoto University Hospital, Kyoto, Japan.
Shigehito YamadaClinical Genetics Unit, Kyoto University Hospital, Kyoto, Japan.ORCID http://orcid.org/0000-0002-8194-6927
Yosuke FujiiUnit of Statistical Genetics, Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hideaki SawaiDepartment of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan.
Naoko ArimoriThe School of Health Sciences, Niigata University, Niigata, Japan.
Yasuko YamanouchiDepartment of Social Work, Faculty of Health and Welfare, Kawasaki University of Medical Welfare, Kurashiki, Japan.
Yuka OzasaDepartment of Nursing, Tokyo Medical and Dental University Medical Hospital, Tokyo, Japan.
Makoto KanaiDepartment of Family and Child Nursing, and Midwifery, Shinshu University School of Health Sciences, Matsumoto, Japan.
Haruhiko SagoCenter of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Akihiko SekizawaDepartment of Obstetrics and Gynecology, School of Medicine, Showa University, Tokyo, Japan.
Fumio TakadaDepartment of Medical Genetics and Genomics, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.ORCID http://orcid.org/0000-0003-4038-4275
Hideaki MasuzakiDepartment of Obstetrics and Gynecology, Nagasaki University, Nagasaki, Japan.
Yoichi MatsubaraNational Research Institute for Child Health and Development, Tokyo, Japan.
Fumiki HiraharaNational Hospital Organization Yokohama Medical Center, Yokohama, Japan.
Koji KuguDepartment of Obstetrics and Gynecology, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal testing has been provided in Japan over the past several decades. However, it is difficult to assess the clinical status of amniocentesis (AC) and maternal serum markers (MSM) because obstetricians can perform these tests without registration. This study aims to investigate the current clinical status of AC and MSM in Japan. We conducted a questionnaire study that was intended for a total of 5622 Japanese obstetrics/gynecology facilities during October 2013 to January 2014. The response rate was 40.8% (2295/5622). Of the 2295 facilities, 864 performed MSM (37.7%), 619 performed AC (27.0%) and 412 performed both (18.0%). The average number of MSM tests was 2.0 per month (range 0-52), and the average number of AC tests was 2.4 per month (range 0-30). Involvement of genetic professionals, such as clinical geneticists (CGs) and certified genetic counselors (CGCs), contribute to a content-rich explanation and management of difficult issues and lengthened the explanation time. Nevertheless, relatively few facilities employed these specialists (MSM: 96/864 and AC: 128/619). This is the first study to highlight the current clinical status of AC and MSM tests in Japan. Active involvement of CGs and CGCs can provide more appropriate genetic counseling for prenatal tests.

Indexed as

AmniocentesisBiomarkersHealth Care SurveysPrenatal DiagnosisFemaleGenetic TestingHealth PersonnelHumansJapanPregnancyProfessional-Patient RelationsSurveys and QuestionnairesBiomarkers

Identifiers

PMID27357425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.