ArticleEpidemiology and infection2016
Multilocus sequence typing and CTX-M characterization of ESBL-producing E. coli: a prospective single-centre study in Lower Saxony, Germany.
Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages.Clinical microbiology reviews · 2019Pooled it
- Integration sites ofFrontiers in microbiology · 2025Article
- Colostrum as a source of ESBL-Escherichia coli in feces of newborn calves.Scientific reports · 2024Article
- Extended-Spectrum ß-Lactamase-ProducingMicroorganisms · 2022Article
- Genetic evaluation of ESBL-producingJAC-antimicrobial resistance · 2021Article
- Whole Genome Sequencing Analysis of Porcine Faecal CommensalMicroorganisms · 2020Article
- Virulence Potential of a Multidrug-ResistantMicroorganisms · 2020Article
- Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production - a threat around the world.Heliyon · 2020Review
- Dissemination of Multidrug-Resistant CommensalFrontiers in microbiology · 2019Article
- Dissemination and persistence of extended-spectrum cephalosporin-resistance encoding IncI1-blaThe ISME journal · 2018Article
- Whole genome sequencing, molecular typing and in vivo virulence of OXA-48-producing Escherichia coli isolates including ST131 H30-Rx, H22 and H41 subclones.Scientific reports · 2017Article
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Authors and funding
4 authors.
Funding
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Abstract
The increasing prevalence of extended-spectrum β-lactamase (ESBL)-producing Gram-negative bacteria is a serious threat for current healthcare settings. In this study we investigated the molecular epidemiology of ESBL-producing E. coli at the University Medical Center Göttingen in Lower Saxony, Germany. All E. coli isolates with an ESBL phenotype were collected during a 6-month period in 2014. Multilocus sequence typing and CTX-M characterization were performed on 160 isolates. Of the ESBL-producing isolates 95·6% were CTX-M positive. Compared to recent Germany-wide studies, we found CTX-M-1 to occur in higher frequency than CTX-M-15 (44·4% vs. 34·4%). CTX-M-14 and CTX-M-27 were detected at 9·4% and 5·0%, respectively. The globally dominant sequence type (ST) 131, which is often associated with CTX-M-15, occurred at a relatively low rate of 24%. Major non-ST131 sequence types were ST101 (5%), ST58 (5%), ST10 (4·4%), ST38 (4·4%), ST410 (3·8%) and ST453 (3·1%). Several of these major sequence types were previously shown to be associated with livestock farming. Together, our study indicates that E. coli lineage distribution in individual healthcare settings can significantly differ from average numbers obtained in nationwide studies.
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