Evidence map›Paper›PMID 27357175›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2016

Bone Mineral Density Is Positively Related to Carotid Intima-Media Thickness: Findings From a Population-Based Study in Adolescents and Premenopausal Women.

Monika Frysz, Kevin Deere, Debbie A Lawlor, Li Benfield, Jon H Tobias, Celia L Gregson

Open access · hybridAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Circulating Sclerostin Levels Are Positively Related to Coronary Artery Disease Severity and Related Risk Factors.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  6. Low bone mineral density and coronary artery disease: A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2021
    Review
  7. Article
  8. Article
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  11. The associations of subclinical atherosclerotic cardiovascular disease with hip fracture risk and bone mineral density in elderly adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Monika FryszSchool of Social and Community Medicine, University of Bristol, MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Kevin DeereMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Debbie A LawlorSchool of Social and Community Medicine, University of Bristol, MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Li BenfieldSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Jon H TobiasMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
Celia L GregsonMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.
University of Bristol · GBNIHR Oxford Musculoskeletal Biomedical Research Centre · GB

Funding

Arthritis Research UK 20000British Heart Foundation SP/07/008/24066Medical Research Council G1001357Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/5Wellcome Trust 102215Wellcome Trust 102215/2/13/2Wellcome Trust 105504/Z/14/ZWellcome Trust WT092830M
6 · The paper itself

Abstract

Osteoporosis and cardiovascular disease (CVD) are both common causes of morbidity and mortality. Previous studies, mainly of people older than 60 years, suggest a relationship between these conditions. Our aim was to determine the association between bone characteristics and CVD markers in younger and middle-aged individuals. Women (n = 3366) and their adolescent offspring (n = 4368) from the UK population-based cohort study, Avon Longitudinal Study of Parents and Children (ALSPAC), were investigated. We measured total body (TB) and hip bone mineral density (BMD), TB bone area (BA) and bone mineral content (BMC) by dual-energy X-ray absorptiometry (DXA), and carotid intima-media thickness (cIMT) by high-resolution ultrasound. Arterial distensibility was calculated as the difference between systolic and diastolic arterial diameters. Linear regression determined associations between bone exposures and cIMT (in adolescents) and both cIMT and arterial distensibility (in women), generating partial correlation coefficients. Mean (SD) age of women was 48 (4.2) years, body mass index (BMI) was 26.2 (5.0) kg/m

Indexed as

Bone DensityCarotid Intima-Media ThicknessAbsorptiometry, PhotonAdolescentAdultArteriesCohort StudiesFemaleHipHumansPremenopauseALSPACATHEROSCLEROSISBONE MINERAL DENSITYCARDIOVASCULAR DISEASEOSTEOPOROSIS

Identifiers

PMID27357175
PMCPMC5244498
OpenAlexW2471507535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.