ArticleHeart (British Cardiac Society)2016
Psychological stress and short-term hospitalisations or death in patients with heart failure.
Article in Heart (British Cardiac Society), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Stress management interventions for adults with heart failure: Systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Pooled it
- Autonomic Imbalance in Cardiomyopathy and Heart Failure: From Neurobiology to Precision Neuromodulation.Current cardiology reports · 2025Review
- The Role of Stress in Venipuncture Pain in Adolescents: Secondary Analysis of a Prospective Observational Study.Children (Basel, Switzerland) · 2025Article
- Dysregulated RBM24 phosphorylation impairs APOE translation underlying psychological stress-induced cardiovascular disease.Nature communications · 2024Article
- The Perceived Stress Scale as a Measure of Stress: Decomposing Score Variance in Longitudinal Behavioral Medicine Studies.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Observational
- Developing and Implementing an mHealth Heart Failure Self-care Program to Reduce Readmissions: Randomized Controlled Trial.JMIR cardio · 2022Article
- Contemporary economic burden in a real-world heart failure population with Commercial and Medicare supplemental plans.Clinical cardiology · 2021Article
- Psychological stress in heart failure: a potentially actionable disease modifier.Heart failure reviews · 2021Review
- Associations of perceived stress and state anger with symptom burden and functional status in patients with heart failure.Psychology & health · 2019Article
- Psychosocial Stress and Cardiovascular Disease.Current treatment options in cardiovascular medicine · 2019Review
- Anger, hostility, and hospitalizations in patients with heart failure.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017Article
- A New Clinically Applicable Measure of Functional Status in Patients With Heart Failure: The 60-Foot Walk Test.JACC. Heart failure · 2017Observational
- Perceived Stress After Acute Myocardial Infarction: A Comparison Between Young and Middle-Aged Women Versus Men.Psychosomatic medicine · 2017Article
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 2 countries.
Funding
Abstract
objectiveStandard predictors do not fully explain variations in the frequency and timing of heart failure (HF) adverse events (AEs). Psychological stress can trigger acute cardiovascular (CV) events, but it is not known whether stress can precipitate AEs in patients with HF. We investigated prospective associations of psychological stress with AEs in patients with HF.
methods144 patients with HF (77% male; 57.5±11.5, range 23-87 years, left ventricular ejection fraction ≤40%) were longitudinally evaluated for psychological stress (Perceived Stress Scale) and AEs (CV hospitalisations/death) at 2-week intervals for 3 months and at 9-month follow-up.
results42 patients (29.2%) had at least one CV hospitalisation and nine (6.3%) died. Patients reporting high average perceived stress across study measurements had a higher likelihood of AEs during the study period compared with those with lower stress (odds ratio=1.10, 95% confidence interval=1.04 to 1.17). In contrast to average levels, increases in stress did not predict AEs (p=0.96). Perceived stress was elevated after a CV hospitalisation (B=2.70, standard error (SE)=0.93, p=0.004) suggesting that CV hospitalisations increase stress. Subsequent analysis indicated that 24 of 38 (63%) patients showed a stress increase following hospitalisation. However, a prospective association between stress and AEs was present when accounting for prior hospitalisations (B=2.43, SE=1.23, p=0.05).
conclusionsSustained levels of perceived stress are associated with increased risk of AEs, and increased distress following hospitalisation occurs in many, but not all, patients with HF. Patients with chronically high stress may be an important target group for HF interventions aimed at reducing hospitalisations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.