Evidence map›Paper›PMID 27355526›Full record

Trial reportCritical care medicine2016

Randomized Trial of Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults.

David R Janz, Matthew W Semler, Robert J Lentz, Daniel T Matthews, Tufik R Assad, Brett C Norman, Raj D Keriwala, Benjamin A Ferrell, Michael J Noto, Ciara M Shaver and 4 more

2 registry-linked trialsAbstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 62 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04242966 phase3withdrawnnot on this mapstarted 2020, after this paper: background citation

The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Registry-based Randomized Trial: The EFFORT Ultrasound a Sub-study

TypeinterventionalSponsorClinical Evaluation Research Unit at Kingston General HospitalRan2020 to 2022Enrolled0ConditionsCritical Illness, MalnutritionArmsUsual Care, Higher Protein/Amino Acid Group, Ultrasound measure
NCT05520762 narecruitingnot on this mapstarted 2023, after this paper: background citation

Hospital Airway Resuscitation Trial: A Cluster-Randomized, Pragmatic Trial

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2027Enrolled1,060ConditionsCardiac Arrest, Respiratory FailureArmsA strategy of first choice supraglottic airway, A strategy of first choice endotracheal intubation
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  17. Preoperative X-ray CBMC anesthesiology · 2021
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

David R Janz1Department of Medicine, Section of Pulmonary and Critical Care Medicine Louisiana State University School of Medicine, New Orleans, LA. 2Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
Matthew W Semler
Robert J Lentz
Daniel T Matthews
Tufik R Assad
Brett C Norman
Raj D Keriwala
Benjamin A Ferrell
Michael J Noto
Ciara M Shaver
Bradley W Richmond
Jeannette Zinggeler Berg
Todd W Rice
Facilitating EndotracheaL intubation by Laryngoscopy technique and apneic Oxygenation Within the ICU Investigators and the Pragmatic Critical Care Research Group

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Building Interdisciplinary Research Careers in Women's HealthK12HD043483 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARTMANN, KATHERINE E, MAJOR, AMY S · 2002 to 2023
$10.3M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
NCATS NIH HHS KL2 TR000446NCATS NIH HHS UL1 TR000445NHLBI NIH HHS T32 HL087738NICHD NIH HHS K12 HD043483
6 · The paper itself

Abstract

objectiveTo evaluate the effect of video laryngoscopy on the rate of endotracheal intubation on first laryngoscopy attempt among critically ill adults.

designA randomized, parallel-group, pragmatic trial of video compared with direct laryngoscopy for 150 adults undergoing endotracheal intubation by Pulmonary and Critical Care Medicine fellows.

settingMedical ICU in a tertiary, academic medical center. PATIENTS: Critically ill patients 18 years old or older.

interventionsPatients were randomized 1:1 to video or direct laryngoscopy for the first attempt at endotracheal intubation. MEASUREMENTS AND MAIN

resultsPatients assigned to video (n = 74) and direct (n = 76) laryngoscopy were similar at baseline. Despite better glottic visualization with video laryngoscopy, there was no difference in the primary outcome of intubation on the first laryngoscopy attempt (video 68.9% vs direct 65.8%; p = 0.68) in unadjusted analyses or after adjustment for the operator's previous experience with the assigned device (odds ratio for video laryngoscopy on intubation on first attempt 2.02; 95% CI, 0.82-5.02, p = 0.12). Secondary outcomes of time to intubation, lowest arterial oxygen saturation, complications, and in-hospital mortality were not different between video and direct laryngoscopy.

conclusionsIn critically ill adults undergoing endotracheal intubation, video laryngoscopy improves glottic visualization but does not appear to increase procedural success or decrease complications.

Indexed as

Critical IllnessVideo RecordingAcademic Medical CentersAgedCarbon DioxideFemaleHospital MortalityHumansIntensive Care UnitsIntubation, IntratrachealLaryngoscopyLength of StayMaleMiddle AgedOxygenProspective StudiesCarbon DioxideOxygen

Identifiers

PMID27355526
PMCPMC5203695

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.