ArticlePloS one2016
Propionibacterium avidum as an Etiological Agent of Prosthetic Hip Joint Infection.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03849885 (Cutibacterium Dermal Colonization), which is not on this map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty
Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
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- Cutibacterium avidum resists surgical skin antisepsis in the groin-a potential risk factor for periprosthetic joint infection: a quality control study.Antimicrobial resistance and infection control · 2021Article
- Diagnosis of orthopaedic-implant-associated infections caused by slow-growing Gram-positive anaerobic bacteria - a clinical perspective.Journal of bone and joint infection · 2021Review
- Revealing antimicrobial resistance in stormwater with MinION.Chemosphere · 2020Article
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- Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium)Clinical microbiology reviews · 2018Review
- Propionibacterium avidum: A Virulent Pathogen Causing Hip Periprosthetic Joint Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Orthopedic implant-associated infections caused by Cutibacterium spp. - A remaining diagnostic challenge.PloS one · 2018Article
- Toward a Metagenomic Understanding on the Bacterial Composition and Resistome in Hong Kong Banknotes.Frontiers in microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (PJIs). Other Propionibacterium spp. have occasionally been described as a cause of PJIs, but this has not previously been the case for P. avidum despite its capacity to form biofilm. We describe two patients with prosthetic hip joint infections caused by P. avidum. Both patients were primarily operated with an anteriorly curved skin incision close to the skin crease of the groin, and both were obese. Initial treatment was performed according to the DAIR procedure (debridement, antibiotics, and implant retention). In case 1, the outcome was successful, but in case 2, a loosening of the cup was present 18 months post debridement. The P. avidum isolate from case 1 and two isolates from case 2 (obtained 18 months apart) were selected for whole genome sequencing. The genome of P. avidum obtained from case 1 was approximately 60 kb larger than the genomes of the two isolates of case 2. These latter isolates were clonal with the exception of SNPs in the genome. All three strains possessed the gene cluster encoding exopolysaccharide synthesis. P. avidum has a pathogenic potential and the ability to cause clinically relevant infections, including abscess formation, in the presence of foreign bodies such as prosthetic joint components. Skin incision in close proximity to the groin or deep skin crease, such as the anteriorly curved skin incision approach, might pose a risk of PJIs by P. avidum, especially in obese patients.
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Registered trials
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