ArticlePhysiological reports2016
Pericardial patch venoplasty heals via attraction of venous progenitor cells.
Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- The needle-puncture mouse aortocaval AVF model: a state of the art review.Renal failure · 2026Review
- From Acute Thrombosis to Eccentric Neointima in Arteriovenous Fistula.Seminars in thrombosis and hemostasis · 2026Article
- Early thrombus formation is required for eccentric and heterogeneous neointimal hyperplasia under disturbed flow.Journal of thrombosis and haemostasis : JTH · 2024Article
- Multilineage commitment of Sca-1Theranostics · 2023Article
- Delivery of rivaroxaban and chitosan rapamycin microparticle with dual antithrombosis and antiproliferation functions inhibits venous neointimal hyperplasia.Drug delivery · 2022Article
- The application of tissue-engineered fish swim bladder vascular graft.Communications biology · 2021Article
- Article
- A Novel Plant Leaf Patch Absorbed With IL-33 Antibody Decreases Venous Neointimal hyperplasia.Frontiers in bioengineering and biotechnology · 2021Article
- Molecular identity of arteries, veins, and lymphatics.Journal of vascular surgery · 2019Review
- Polyester vascular patches acquire arterial or venous identity depending on their environment.Journal of biomedical materials research. Part A · 2017Article
- Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency.Scientific reports · 2017Article
- Dual Function for Mature Vascular Smooth Muscle Cells During Arteriovenous Fistula Remodeling.Journal of the American Heart Association · 2017Article
- Patch Angioplasty in the Rat Aorta or Inferior Vena Cava.Journal of visualized experiments : JoVE · 2017Article
- Covalent modification of pericardial patches for sustained rapamycin delivery inhibits venous neointimal hyperplasia.Scientific reports · 2017Article
- Pericardial patch venoplasty heals via attraction of venous progenitor cells.Physiological reports · 2016Article
- Autologous tissue patches acquire vascular identity depending on the environment.Vascular investigation and therapyArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
Pericardial patches are commonly used during cardiovascular surgery to close blood vessels. In arteries, patches accumulate arterial progenitor cells; we hypothesized that venous patches would accumulate venous progenitor cells, in the absence of arterial pressure. We developed a novel rat inferior vena cava (IVC) venotomy model and repaired it with a pericardial patch. Cells infiltrated the patch to form a thick neointima by day 7; some cells were CD34(+)/VEGFR2(+) and CD31(+)/Eph-B4(+) consistent with development of venous identity in the healing patch. Compared to arterial patches, the venous patches had increased neointimal thickness at day 7 without any pseudoaneurysms. Addition of an arteriovenous fistula (AVF) to increase blood flow on the patch resulted in reduced patch neointimal thickness and proliferation, but neointimal thickness was not reversible with AVF ligation. These results show that rat patch venoplasty is a novel model of aggressive venous neointimal hyperplasia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.