Evidence map›Paper›PMID 27353724›Full record

ArticleTropical medicine & international health : TM & IH2016

Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique.

Alicia A Annamalay, Miguel Lanaspa, Siew-Kim Khoo, Lola Madrid, Sozinho Acácio, Guicheng Zhang, Ingrid A Laing, James Gern, Jack Goldblatt, Joelene Bizzintino and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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  15. Viral infections in wheezing disorders.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Alicia A AnnamalaySchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Miguel LanaspaCentro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
Siew-Kim KhooSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Lola MadridCentro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
Sozinho AcácioCentro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
Guicheng ZhangSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Ingrid A LaingSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
James GernUniversity of Wisconsin-Madison, Madison, WI, USA.
Jack GoldblattSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Joelene BizzintinoSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Deborah LehmannTelethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
Peter N Le SouëfSchool of Paediatrics and Child Health, The University of Western Australia, Perth, WA, Australia.
Quique BassatCentro de Investigação em Saúde de Manhiça, Maputo, Mozambique.
University of Western Australia · AUThe Kids Research Institute Australia · AUManhiça Health Research Centre · MZBarcelona Institute for Global Health · ESUniversitat de Barcelona · ESUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the prevalence of human rhinovirus (RV) species in children hospitalised with pneumonia in Manhiça, Mozambique, and the associations between RV species and demographic, clinical and laboratory features.

methodsNasopharyngeal aspirates were collected from children 0 to 10 years of age (n = 277) presenting to Manhiça District Hospital with clinical pneumonia. Blood samples were collected for HIV and malaria testing, blood culture and full blood counts, and a chest X-ray was performed. A panel of common respiratory viruses was investigated using two independent multiplex RT-PCR assays with primers specific for each virus and viral type. RV species and genotypes were identified by seminested PCR assays, sequencing and phylogenetic tree analyses.

resultsAt least one respiratory virus was identified in 206 (74.4%) children hospitalised with clinical pneumonia. RV was the most common virus identified in both HIV-infected (17 of 38, 44.7%) and HIV-uninfected (74 of 237, 31.2%; P = 0.100) children. RV-A was the most common RV species identified (47 of 275, 17.0%), followed by RV-C (35/275, 12.6%) and RV-B (8/275, 2.9%). Clinical presentation of the different RV species was similar and overlapping, with no particular species being associated with specific clinical features.

conclusionsRV-A and RV-C were the most common respiratory viruses identified in children hospitalised with clinical pneumonia in Manhiça. Clinical presentation of RV-A and RV-C was similar and overlapping.

Indexed as

GenotypeHospitalizationChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMozambiqueMultiplex Polymerase Chain ReactionPhylogenyPneumoniaPrevalenceRhinovirusSpecies SpecificitychildrenenfantsMozambiqueneumoníaniñospneumoniapneumonierhinovirus

Identifiers

PMID27353724
PMCPMC7169728
OpenAlexW2475176108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.