Evidence map›Paper›PMID 27353703›Full record

ArticleScientific reports2016

Protein-directed synthesis of highly monodispersed, spherical gold nanoparticles and their applications in multidimensional sensing.

Yumin Leng, Ling Fu, Liqun Ye, Bo Li, Xiumei Xu, Xiaojing Xing, Junbao He, Yuling Song, Chaoliang Leng, Yongming Guo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 90 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yumin LengCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Ling FuCollege of Agricultural Engineering, Nanyang Normal University, Nanyang 473061, China.
Liqun YeCollege of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
Bo LiCollege of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
Xiumei XuCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Xiaojing XingCollege of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
Junbao HeCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Yuling SongCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Chaoliang LengCollege of Agricultural Engineering, Nanyang Normal University, Nanyang 473061, China.
Yongming GuoCollege of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
Xiaoxu JiCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Zhiwen LuCollege of Physics and Electronic Engineering, Nanyang Normal University, Nanyang 473061, China.
Nanyang Normal University · CNAnyang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An in-situ reduction method has been reported to prepare gold nanoparticles (GNPs) of 40-110 nm by using the green reducing agents of proteins, which are activated by H2O2 and the superoxide anion (). The protein of collagen turns HAuCl4 to the aqueous Au(I) ainions, which are further reduced by other proteins to be highly monodispersed and spherical GNPs of different sizes. The GNPs reduced by different proteins are found to be with the exposed {100} facets, the distinctive UV-vis absorption spectra and various colors (See Fig. 1). By means of extracting the color responses, such as red, green and blue (RGB) alterations, an in-situ reduction method-based multidimensional sensing platform is fabricated in the process of GNPs synthesis. Without further modification of GNPs, nine common proteins are found to be well detected and discriminated at different concentrations. Moreover, this sensing platform also demonstrates great potentials in qualitative and semiquantitative analysis on the individuals of these proteins with high sensitivity. Furthermore, the validation of this multidimensional sensing platform has been carried out by analysis on the spiked proteins in human urine and the target proteins in complex matrix (e.g. lysozyme in human tear).

Indexed as

Coloring AgentsGoldHumansHydrogen PeroxideLimit of DetectionMetal NanoparticlesOxidation-ReductionProteinsSolutionsTearsUrinalysisColoring AgentsGoldHydrogen PeroxideProteinsSolutions

Identifiers

PMID27353703
PMCPMC4926111
OpenAlexW2461758920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.