ArticleScientific reports2016
Identification and expression profiles of neuropeptides and their G protein-coupled receptors in the rice stem borer Chilo suppressalis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 63 citations in OpenAlex.
- Identification of Neuropeptide F (NPF) Signaling and Associated Regulation of Food Intake in the Dark Black Chafer BeetleBiology · 2026Article
- A brain-gut excitatory peptide/CCHamide homolog regulates satiation and motivational state transitions in the Aplysia feeding circuit.The Journal of biological chemistry · 2026Article
- Exploration of neuropeptides to identify potential target for regulating feeding behavior and development in Eurygaster integriceps.PloS one · 2026Article
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- The genome and sex-dependent responses to temperature in the common yellow butterfly, Eurema hecabe.BMC biology · 2023Article
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- Mass Spectrometric Proof of Predicted Peptides: Novel Adipokinetic Hormones in Insects.Molecules (Basel, Switzerland) · 2022Article
- G-Protein Coupled Receptors (GPCRs) in Insects-A Potential Target for New Insecticide Development.Molecules (Basel, Switzerland) · 2021Review
- Functional Identification and Characterization of Leucokinin and Its Receptor in the Fall Webworm,Frontiers in physiology · 2021Article
- Cloning and Expression of the Neuropeptide F and Neuropeptide F Receptor Genes and Their Regulation of Food Intake in the Chinese White Pine BeetleFrontiers in physiology · 2021Article
- Pharmacological Characterization of the Stick InsectACS omega · 2020Article
- Identification of Neuropeptides and Their Receptors in the Ectoparasitoid,Frontiers in physiology · 2020Article
- Neuropeptides and G-Protein Coupled Receptors (GPCRs) in the Red Palm WeevilFrontiers in physiology · 2020Article
- Identifying Neuropeptide and G Protein-Coupled Receptors of Juvenile Oriental River Prawn (Frontiers in endocrinology · 2020Article
- Identification and Characterization of Neuropeptides and Their G Protein-Coupled Receptors (GPCRs) in the Cowpea AphidFrontiers in endocrinology · 2020Article
- Unique Members of the Adipokinetic Hormone Family in Butterflies and Moths (Insecta, Lepidoptera).Frontiers in physiology · 2020Article
- Prediction and expression analysis of G protein-coupled receptors in the laboratory stick insect, Carausius morosus.Turkish journal of biology = Turk biyoloji dergisi · 2019Article
- Characterization and Expression Profiling of Neuropeptides and G-Protein-Coupled Receptors (GPCRs) for Neuropeptides in the Asian Citrus Psyllid,International journal of molecular sciences · 2018Article
- Transcriptomic analysis of crustacean neuropeptide signaling during the moult cycle in the green shore crab, Carcinus maenas.BMC genomics · 2018Article
- Insights Into Sexual Maturation and Reproduction in the Norway Lobster (Frontiers in endocrinology · 2018Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In insects, neuropeptides play important roles in the regulation of multiple physiological processes by binding to their corresponding receptors, which are primarily G protein-coupled receptors (GPCRs). The genes encoding neuropeptides and their associated GPCRs in the rice stem borer Chilo suppressalis were identified by a transcriptomic analysis and were used to identify potential targets for the disruption of physiological processes and the protection of crops. Forty-three candidate genes were found to encode the neuropeptide precursors for all known insect neuropeptides except for arginine-vasopressin-like peptide (AVLP), CNMamide, neuropeptide-like precursors 2-4 (NPLP2-4), and proctolin. In addition, novel alternative splicing variants of three neuropeptide genes (allatostatin CC, CCHamide 1, and short neuropeptide F) are reported for the first time, and 51 putative neuropeptide GPCRs were identified. Phylogenetic analyses demonstrated that 44 of these GPCRs belong to the A-family (or rhodopsin-like), 5 belong to the B-family (or secretin-like), and 2 are leucine-rich repeat-containing GPCRs. These GPCRs and their likely ligands were also described. qRT-PCR analyses revealed the expression profiles of the neuropeptide precursors and GPCR genes in various tissues of C. suppressalis. Our study provides fundamental information that may further our understanding of neuropeptidergic signaling systems in Lepidoptera and aid in the design of peptidomimetics, pseudopeptides or small molecules capable of disrupting the physiological processes regulated by these signaling molecules and their receptors.
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