ArticleScientific reports2016
Holographic microscopy and microfluidics platform for measuring wall stress and 3D flow over surfaces textured by micro-pillars.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Deciphering viscoelastic cell manipulation in rectangular microchannels.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
- Bio-inspired microfluidics: A review.Biomicrofluidics · 2023Review
- Bactericidal efficiency of micro- and nanostructured surfaces: a critical perspective.RSC advances · 2021Review
- Bacteria forming drag-increasing streamers on a drop implicates complementary fates of rising deep-sea oil droplets.Scientific reports · 2020Article
- A new ecology-on-a-chip microfluidic platform to study interactions of microbes with a rising oil droplet.Scientific reports · 2019Article
- Engineered bio-inspired coating for passive flow control.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Label-free fingerprinting of tumor cells in bulk flow using inline digital holographic microscopy.Biomedical optics express · 2017Article
- Holography applications toward medical field: An overview.The Indian journal of radiology & imagingArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Understanding how fluid flow interacts with micro-textured surfaces is crucial for a broad range of key biological processes and engineering applications including particle dispersion, pathogenic infections, and drag manipulation by surface topology. We use high-speed digital holographic microscopy (DHM) in combination with a correlation based de-noising algorithm to overcome the optical interference generated by surface roughness and to capture a large number of 3D particle trajectories in a microfluidic channel with one surface patterned with micropillars. It allows us to obtain a 3D ensembled velocity field with an uncertainty of 0.06% and 2D wall shear stress distribution at the resolution of ~65 μPa. Contrary to laminar flow in most microfluidics, we find that the flow is three-dimensional and complex for the textured microchannel. While the micropillars affect the velocity flow field locally, their presence is felt globally in terms of wall shear stresses at the channel walls. These findings imply that micro-scale mixing and wall stress sensing/manipulation can be achieved through hydro-dynamically smooth but topologically rough micropillars.
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Registered trials
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