Evidence map›Paper›PMID 27353196›Full record

ArticleJournal of veterinary internal medicine2016

Tick-Borne Relapsing Fever in Dogs.

J Piccione, G J Levine, C A Duff, G M Kuhlman, K D Scott, M D Esteve-Gassent

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Biology · 2021
    Review
  7. Article
  8. Article
  9. Prevalence of common tick-borne pathogens in white-tailed deer and coyotes in south Texas.International journal for parasitology. Parasites and wildlife · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. ACVIM consensus update on Lyme borreliosis in dogs and cats.Journal of veterinary internal medicine · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

J PiccioneTexas A&M Veterinary Medical Diagnostic Laboratory, Texas A&M University, College Station, TX.
G J LevineDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX.
C A DuffDepartment of Small Animal Clinical Sciences , College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX.
G M KuhlmanDepartment of Small Animal Clinical Sciences , College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX.
K D ScottDepartment of Small Animal Clinical Sciences , College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX.
M D Esteve-GassentDepartment of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX.
Texas A&M University · USTexas College · US

Funding

Population Genetic Structure of Ixodes scapularis and disease transmissionR21AI107380 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI CASTRO-ARELLANO, IVAN, ESTEVE-GASSENT, MARIA D · 2015 to 2016
$386k
NIAID NIH HHS R21 AI107380
6 · The paper itself

Abstract

backgroundIn the United States, Tick-Borne Relapsing Fever (TBRF) in dogs is caused by the spirochete bacteria Borrelia turicatae and Borrelia hermsii, transmitted by Ornithodoros spp. ticks. The hallmark diagnostic feature of this infection is the visualization of numerous spirochetes during standard blood smear examination. Although the course of spirochetemia has not been fully characterized in dogs, in humans infected with TBRF the episodes of spirochetemia and fever are intermittent.

objectivesTo describe TBRF in dogs by providing additional case reports and reviewing the disease in veterinary and human medicine. ANIMALS: Five cases of privately-owned dogs naturally infected with TBRF in Texas are reviewed.

methodsCase series and literature review.

resultsAll dogs were examined because of lethargy, inappetence, and pyrexia. Two dogs also had signs of neurologic disease. All dogs had thrombocytopenia and spirochetemia. All cases were administered tetracyclines orally. Platelet numbers improved and spirochetemia and pyrexia resolved in 4 out of 5 dogs, where follow-up information was available. CONCLUSION AND CLINICAL IMPORTANCE: TBRF is likely underdiagnosed in veterinary medicine. In areas endemic to Ornithodoros spp. ticks, TBRF should be considered in dogs with thrombocytopenia. Examination of standard blood smears can provide a rapid and specific diagnosis of TBRF when spirochetes are observed.

Indexed as

AnimalsAnti-Bacterial AgentsBorrelia InfectionsDiagnosis, DifferentialDog DiseasesDogsFemaleMaleRelapsing FeverTicksAnti-Bacterial AgentsBacteremiaBorreliaSpirocheteSpirochetemiaThrombocytopenia

Identifiers

PMID27353196
PMCPMC5094544
OpenAlexW2472292666

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.