ArticleProteins2016
Novel proteases from the genome of the carnivorous plant Drosera capensis: Structural prediction and comparative analysis.
Article in Proteins, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Jasmonate signaling and prey nutrient availability trigger distinct biochemical responses in the Drosera capensis feeding cycle.Plant physiology · 2026Article
- A chromosome-scale genome of Sarracenia purpurea reveals a significant expansion of plant defense and stress response gene families following paleopolyploidization.The plant genome · 2026Article
- A high quality genome of the common swamp pitcher plant (Nepenthes mirabilis) using PacBio HiFi sequencing.PloS one · 2025Article
- Molecular Phylogenomics Reveals the Deep Evolutionary History of Carnivory across Land Plants.Plants (Basel, Switzerland) · 2023Review
- Omics Approaches in Uncovering Molecular Evolution and Physiology of Botanical Carnivory.Plants (Basel, Switzerland) · 2023Review
- Snatching Sundews-Analysis of Tentacle Movement in Two Species ofPlants (Basel, Switzerland) · 2022Article
- Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy.Nature communications · 2022Article
- Genome-Wide Analyses of Aspartic Proteases on Potato Genome (Plants (Basel, Switzerland) · 2022Article
- Signaling and transport processes related to the carnivorous lifestyle of plants living on nutrient-poor soil.Plant physiology · 2021Review
- Research advances in and prospects of ornamental plant genomics.Horticulture research · 2021Review
- Article
- Annotated genome sequences of the carnivorous plant Roridula gorgonias and a non-carnivorous relative, Clethra arborea.BMC research notes · 2020Article
- The Droserasin 1 PSI: A Membrane-Interacting Antimicrobial Peptide from the Carnivorous PlantBiomolecules · 2020Article
- Genomes of the Venus Flytrap and Close Relatives Unveil the Roots of Plant Carnivory.Current biology : CB · 2020Article
- Protein structure networks provide insight into active site flexibility in esterase/lipases from the carnivorous plant Drosera capensis.Integrative biology : quantitative biosciences from nano to macro · 2018Article
- Evolutionary and structural analyses uncover a role for solvent interactions in the diversification of cocoonases in butterflies.Proceedings. Biological sciences · 2018Article
- Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics.PeerJ · 2018Article
- Current Strategies of Polyploid Plant Genome Sequence Assembly.Frontiers in plant science · 2018Review
- Article
- Long-read sequencing uncovers the adaptive topography of a carnivorous plant genome.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In his 1875 monograph on insectivorous plants, Darwin described the feeding reactions of Drosera flypaper traps and predicted that their secretions contained a "ferment" similar to mammalian pepsin, an aspartic protease. Here we report a high-quality draft genome sequence for the cape sundew, Drosera capensis, the first genome of a carnivorous plant from order Caryophyllales, which also includes the Venus flytrap (Dionaea) and the tropical pitcher plants (Nepenthes). This species was selected in part for its hardiness and ease of cultivation, making it an excellent model organism for further investigations of plant carnivory. Analysis of predicted protein sequences yields genes encoding proteases homologous to those found in other plants, some of which display sequence and structural features that suggest novel functionalities. Because the sequence similarity to proteins of known structure is in most cases too low for traditional homology modeling, 3D structures of representative proteases are predicted using comparative modeling with all-atom refinement. Although the overall folds and active residues for these proteins are conserved, we find structural and sequence differences consistent with a diversity of substrate recognition patterns. Finally, we predict differences in substrate specificities using in silico experiments, providing targets for structure/function studies of novel enzymes with biological and technological significance. Proteins 2016; 84:1517-1533. © 2016 Wiley Periodicals, Inc.
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