ArticleDiabetes care2016
Cardiovascular Autonomic Neuropathy, Sexual Dysfunction, and Urinary Incontinence in Women With Type 1 Diabetes.
Article in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- Prevalence and predictors of erectile dysfunction among men in the diabetes prevention program outcomes study.Journal of diabetes and its complications · 2024Trial
- Diabetic Peripheral Neuropathy and Urological Complications in Type 1 Diabetes: Findings From the Epidemiology of Diabetes Interventions and Complications Study.Diabetes care · 2022Trial
- Diabetic neuropathy: cutting-edge research and future directions.Signal transduction and targeted therapy · 2025Review
- Article
- Prevalence and Risk Factors for Bladder and Bowel Dysfunction in Children With Type 1 Diabetes.Pediatric diabetes · 2025Article
- The comorbidity burden of type 2 diabetes mellitus (T2DM): sex differences and associated factors among 830 cases in North-Eastern Morocco.Diabetology international · 2024Article
- Article
- Cardiovascular health assessed by the new life's essential 8 and the prevalence of urinary incontinence in adults.BMC public health · 2024Article
- Gonadal dysfunction in women with diabetes mellitus.Endocrine · 2024Review
- Prevalence and predictors of female sexual dysfunction among sexually active women in the diabetes prevention program outcomes study.Neurourology and urodynamics · 2024Article
- Urinary symptoms and female sexual dysfunction in women with type 1 diabetes: the role of depression.The journal of sexual medicine · 2023Article
- Urologic complications in diabetes.Journal of diabetes and its complications · 2022Review
- Sexual dysfunction in women with type 1 diabetes in Norway: A qualitative study of women's experiences.Diabetic medicine : a journal of the British Diabetic Association · 2022Article
- The Potential of Current Noninvasive Wearable Technology for the Monitoring of Physiological Signals in the Management of Type 1 Diabetes: Literature Survey.Journal of medical Internet research · 2022Review
- Longitudinal patterns of urinary incontinence and associated predictors in women with type 1 diabetes.Neurourology and urodynamics · 2022Article
- Autonomic neuropathy and urologic complications in diabetes.Autonomic neuroscience : basic & clinical · 2020Review
- Association between type 1 diabetes and female sexual dysfunction.BMC women's health · 2020Article
- Risk factors for sexual dysfunction in Romanian women with type 1 diabetes mellitus and chronic autoimmune thyroiditis: a comparative cross-sectional study.Diabetology & metabolic syndrome · 2020Article
- Sexual Dysfunction in Women Treated for Type 1 Diabetes and the Impact of Coexisting Thyroid Disease.Sexual medicine · 2019Article
- The Impact of Metabolic Syndrome and Its Components on Female Sexual Dysfunction: A Narrative Mini-Review.Current urology · 2019Review
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThis study evaluated associations among cardiovascular autonomic neuropathy (CAN), female sexual dysfunction (FSD), and urinary incontinence (UI) in women with type I diabetes mellitus (T1DM). RESEARCH DESIGN AND
methodsWe studied 580 women with T1DM in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC). CAN was defined as: 1) R-R variation <15 with deep breathing or 2) R-R variation of 15-19.9 plus Valsalva ratio ≤1.5 or a supine-to-standing drop of 10 mmHg in diastolic blood pressure. A Sandvik Severity Index of 3-12 defined UI, and a Female Sexual Function Index (FSFI-R) score ≥22.75 defined FSD. Multivariable models estimated associations among CAN, FSD, and UI.
resultsAt EDIC year 17, FSD was observed in 41% of women and UI in 30%. No statistically significant associations were observed between measures of CAN at DCCT closeout and subsequent report of FSD or UI. At EDIC year 16/17, there was a 53% increased odds of having UI with a Valsalva ratio ≤1.5. At both EDIC year 13/14 and EDIC year 16/17, a 5-unit increase in R-R variation was associated with a 1.11 greater odds of having FSD.
conclusionsIn women with T1DM in the DCCT/EDIC, we found significant increased odds of FSD and UI with specific measures of CAN. In long-standing T1DM, CAN may predict development of FSD and may be a useful surrogate for generalized diabetic autonomic neuropathy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.