Evidence map›Paper›PMID 27352409›Full record

ArticleThe Permanente journal2016

Difference in Effectiveness of Medication Adherence Intervention by Health Literacy Level.

Ashli A Owen-Smith, David H Smith, Cynthia S Rand, Jeffrey O Tom, Reesa Laws, Amy Waterbury, Andrew Williams, William M Vollmer

Registry-linked trialAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Permanente journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01251757 (Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01251757 nacompletednot on this map

Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies (PATIENT)

TypeinterventionalSponsorKaiser PermanenteRan2011 to 2013Enrolled21,752ConditionsDiabetes Mellitus, Cardiovascular DiseaseArmsInteractive Voice Recognition (IVR) phone calls, Educational mailings and follow-up for nonadherence
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashli A Owen-SmithAssistant Professor of Health Management and Policy at the Georgia State University School of Public Health in Atlanta. aowensmith@gsu.edu.
David H SmithSenior Investigator at The Kaiser Permanente Center for Health Research in Portland, OR. david.h.smith@kpchr.org.
Cynthia S RandProfessor of Medicine in the Department of Medicine at the Johns Hopkins School of Medicine in Baltimore, MD. crand@jhmi.edu.
Jeffrey O TomAssistant Clinical Professor in the Department of Pediatrics at the University of Hawaii John A Burns School of Medicine in Honolulu. jotom@hawaii.edu.
Reesa LawsResearch and Data Analytics Center Manager and Technical Research Program Manager at The Kaiser Permanente Center for Health Research in Portland, OR. reesa.laws@kpchr.org.
Amy WaterburyResearch Program Manager at The Kaiser Permanente Center for Health Research in Portland, OR. amy.waterbury@kpchr.org.
Andrew WilliamsFaculty Scientist in the Center for Outcomes Research and Evaluation at the Maine Medical Center Research Institute in Scarborough. aewilliams@mmc.org.
William M VollmerSenior Investigator at The Kaiser Permanente Center for Health Research in Portland, OR. william.vollmer@kpchr.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThere is little research investigating whether health information technologies, such as interactive voice recognition, are effective ways to deliver information to individuals with lower health literacy.

objectiveDetermine the extent to which the impact of an interactive voice recognition-based intervention to improve medication adherence appeared to vary by participants' health literacy level.

designPromoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies (PATIENT) was a randomized clinical trial designed to test the impact, compared with usual care, of 2 technology-based interventions that leveraged interactive voice recognition to promote medication adherence. A 14% subset of participants was sent a survey that included questions on health literacy. This exploratory analysis was limited to the 833 individuals who responded to the survey and provided data on health literacy.

main outcome measuresAdherence to statins and/or angiotensin-converting enzyme inhibitors and/or angiotensin II receptor blockers.

resultsAlthough intervention effects did not differ significantly by level of health literacy, the data were suggestive of differential intervention effects by health literacy level.

conclusionsThe differences in intervention effects for high vs low health literacy in this exploratory analysis are consistent with the hypothesis that individuals with lower health literacy may derive greater benefit from this type of intervention compared with individuals with higher health literacy. Additional studies are needed to further explore this finding.

Indexed as

Health LiteracyHealth PromotionMedication AdherenceAgedCardiovascular DiseasesFemaleHumansMaleMedical InformaticsMiddle AgedProgram EvaluationSurveys and Questionnaires

Identifiers

PMID27352409
PMCPMC4991913

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.