SynthesisSurgical endoscopy2017
Fibrin glue versus staple for mesh fixation in laparoscopic transabdominal preperitoneal repair of inguinal hernia: a meta-analysis and systematic review.
Synthesis in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Glue versus absorbable tacks for mesh fixation in laparoscopic inguinal hernia repair: a systematic review and meta-analysis of postoperative pain and complications.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Glue versus tackers for mesh fixation in laparoscopic inguinal hernia repair: a meta-analysis and trial sequential analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Pooled it
- Autologous fibrin glue (CryoSealSurgery today · 2026Article
- Transabdominal pre-peritoneal hernia repair: risk of operation for recurrence depends on choice of both mesh and fixation device. A study from the Danish Hernia Database.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Recurrence and complications after laparoscopic inguinal hernia repair using a self-adherent mesh: a patient-reported follow-up study.Surgical endoscopy · 2025Article
- Comparison of anatomical polyester mesh without fixation and conventional flat mesh with fixation in laparoscopic total extraperitoneal repair for inguinal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- To close, not to close, or to act bigger? Managing the defect of large direct inguinal hernia to reduce the risk of recurrence during laparoscopic TAPP repair: a retrospective cohort study.Updates in surgery · 2024Article
- Harnessing Non-Thermal Plasma to Supercharge Recovery in Abdominal Surgeries: A Pilot Study.Journal of clinical medicine · 2024Article
- Cyanoacrylate mesh fixation for laparoscopic inguinal hernia repair: a prospective, multicenter, single-arm study.Surgical endoscopy · 2023Article
- Cost-effectiveness analysis of mesh fixation techniques for laparoscopic and open inguinal hernia surgeries.BMC health services research · 2022Article
- Three-point mesh fixation in robot-assisted transabdominal preperitoneal (R-TAPP) repair of 208 inguinal hernias: preliminary results of a single-center consecutive series.Langenbeck's archives of surgery · 2022Article
- Mesh fixation techniques for inguinal hernia repair: an overview of systematic reviews of randomised controlled trials.Hernia : the journal of hernias and abdominal wall surgery · 2022Review
- Laparoscopic inguinal hernia repair: cost-effectiveness analysis of trend modifications of the technique.Updates in surgery · 2021Article
- Predictive factors of post-laparoscopic inguinal hernia acute and chronic pain: prospective follow-up of 807 patients from a single experienced surgeon.Surgical endoscopy · 2021Article
- Long-term outcome and chronic pain in atraumatic fibrin glue versus staple fixation of extra light titanized meshes in laparoscopic inguinal hernia repair (TAPP): a single-center experience.Surgical endoscopy · 2020Article
- Mesh fixation technique for inguinal hernia repair: protocol for an umbrella review with integrated and updated network meta-analysis.BMJ open · 2019Article
- Adhesional small bowel obstruction related to stapling device from previous laparoscopic inguinal hernia repair.BMJ case reports · 2019Article
- What are the influencing factors for chronic pain following TAPP inguinal hernia repair: an analysis of 20,004 patients from the Herniamed Registry.Surgical endoscopy · 2018Article
- Surgical risk factors for recurrence in inguinal hernia repair - a review of the literature.Innovative surgical sciences · 2017Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to compare outcomes of mesh fixation using fibrin glue versus staple in laparoscopic transabdominal preperitoneal (TAPP) repair of inguinal hernia. METHODS AND PROCEDURES: Database searches were carried out in PubMed, Embase, Cochrane Library, Web of Science and Cochrane databases until February 2016 using specific search terms. Studies which compared fibrin glue and staple for mesh fixation in laparoscopic transabdominal preperitoneal repair of inguinal hernia were enrolled. Outcomes, including inguinal hernia recurrence, chronic inguinal pain, seroma or hematoma formation and operating time, were measured.
resultsFour randomized controlled trials (RCTs, 430 patients) and six non-randomized controlled trials (non-RCTs, 8637 patients) were analyzed. Meta-analysis of the four RCTs showed no significant difference in hernia recurrence (OR 2.10, 95 % CI 0.61, 7.22), seroma or hematoma formation (OR 0.55, 95 % CI 0.27, 1.14) and operating time (SMD 0.80, 95 % CI -0.34, 1.94). Similarly, there was no significant difference in most of the outcomes of the six non-RCTs.
conclusionsOur meta-analysis and systematic review shows that the use of fibrin glue fixation may provide an alternative approach to staple fixation in TAPP inguinal hernia repair without increasing the postoperative morbidity. Large-scale RCTs with long-term follow-up are still needed to further assess postoperative outcomes such as chronic pain and disease recurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.