Evidence map›Paper›PMID 27351631›Full record

ArticlePLoS medicine2016

Weighing Evidence from Mendelian Randomization-Early-Life Obesity as a Causal Factor in Multiple Sclerosis?

Alberto Ascherio, Kassandra L Munger

Open access · goldAbstract readComment
In one paragraph

Article in PLoS medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alberto AscherioHarvard T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.
Kassandra L MungerHarvard T. H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.
Harvard University · US

Funding

Vitamin D, Epstein-Barr virus infection, and cigarette smoking and risk of multipR01NS073633 · NINDS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ASCHERIO, ALBERTO · 2011 to 2015
$2.6M
NINDS NIH HHS R01 NS073633
6 · The paper itself

Abstract

In this Perspective, Alberto Ascherio and Kassandra Munger discuss the implications of Richards and colleagues' study exploring the role of early-life obesity in risk of multiple sclerosis.

Indexed as

Body Mass IndexMendelian Randomization AnalysisGenome-Wide Association StudyHumansMultiple SclerosisObesityPolymorphism, Single Nucleotide

Identifiers

PMID27351631
PMCPMC4924836
OpenAlexW2461067290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.