Evidence map›Paper›PMID 27351182›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2016

Noninvasive methods of detecting increased intracranial pressure.

Wen Xu, Patrick Gerety, Tomas Aleman, Jordan Swanson, Jesse Taylor

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03286426 (Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03286426 naterminatednot on this mapstarted 2017, after this paper: background citation

Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure

TypeinterventionalSponsorDuke UniversityRan2017 to 2018Enrolled3ConditionsIntracranial Pressure IncreaseArmsPictor
3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Prediction of intracranial hypertension through noninvasive intracranial pressure waveform analysis in pediatric hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017
    Trial
  2. Article
  3. Advancements in Non-Invasive Intracranial Pressure Monitoring via Optic Nerve Sheath Diameter Measurement.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  4. Article
  5. A coddling of the sagittal suture: inequality in spring-assisted expansion.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  6. Review
  7. Review
  8. Noninvasive intracranial pressure monitoring throughout brain compliance guiding a ventriculoperitoneal shunt replacement in hydrocephalus-case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  9. Article
  10. Normocephalic sagittal craniosynostosis in young children is common and unrecognized.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Non-invasive detection of intracranial pressure related to the optic nerve.Quantitative imaging in medicine and surgery · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. The role of ICP overnight monitoring (ONM) in children with suspected craniostenosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Article
  20. Use of neuroimaging measurements of optic nerve sheath diameter to assess intracranial pressure in craniosynostosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen XuCraniofacial Surgery Center and Division of Plastic Surgery, The Children's Hospital of Philadelphia and the University of Pennsylvania, Colket Translational Research Building, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Patrick GeretyCraniofacial Surgery Center and Division of Plastic Surgery, The Children's Hospital of Philadelphia and the University of Pennsylvania, Colket Translational Research Building, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Tomas AlemanScheie Eye Institute and the Department of Ophthalmology, Perelman Center for Advanced Medicine and the University of Pennsylvania, Philadelphia, PA, USA.
Jordan SwansonCraniofacial Surgery Center and Division of Plastic Surgery, The Children's Hospital of Philadelphia and the University of Pennsylvania, Colket Translational Research Building, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Jesse TaylorCraniofacial Surgery Center and Division of Plastic Surgery, The Children's Hospital of Philadelphia and the University of Pennsylvania, Colket Translational Research Building, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA. taylorj5@email.chop.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of elevated intracranial pressure (ICP) is of paramount importance in the diagnosis and management of a number of neurologic pathologies. The current gold standard is the use of intraventricular or intraparenchymal catheters; however, this is invasive, expensive, and requires anesthesia. On the other hand, diagnosing intracranial hypertension based on clinical symptoms such as headaches, vomiting, and visual changes lacks sensitivity. As such, there exists a need for a noninvasive yet accurate and reliable method for detecting elevated ICP. In this review, we aim to cover both structural modalities such as computed tomography (CT), magnetic resonance imaging (MRI), ocular ultrasound, fundoscopy, and optical coherence tomography (OCT) as well as functional modalities such as transcranial Doppler ultrasound (TCD), visual evoked potentials (VEPs), and near-infrared spectroscopy (NIRS).

Indexed as

Diagnostic ImagingElectroencephalographyEvoked Potentials, VisualHumansIntracranial HypertensionIntracranial PressureNeuroimagingNoninvasive intracranial pressureOptical coherence tomographyOptic nerve sheath diameterPapilledemaTranscranial Doppler ultrasoundVisual evoked potentials

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.